Stanford is home to CAR-T innovation (Mackall, Majzner), the CD47 discovery (Weissman), and AI in medicine.
Stanford Health Care and the Stanford Cancer Institute in California hold NCI comprehensive designation and thirtieth place in the Newsweek/Statista oncology ranking, and they matter for CAR-T innovation, the CD47 discovery and AI in medicine. Crystal L. Mackall and Majzner developed GD2 CAR-T for diffuse intrinsic pontine glioma, Irving L. Weissman's CD47 work is the origin of magrolimab, Adler invented the CyberKnife, and Ronald Levy leads its lymphoma tradition, with Ash A. Alizadeh, Christina Curtis and Heather A. Wakelee also listed. OnCo links it to Evo 2, GenePT and the Merlin CT vision-language model, to pathways from chromosomal instability to ferroptosis, and to funders including the Chan Zuckerberg Biohub and the Parker Institute. Getting CAR-T past the blood-brain barrier durably is the bottleneck its glioma work confronts. Programmes and people are listed below.
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-24.
Matched to Stanford University, including child institutions. 3,016 works · 50,896 citations · 69% open access · 10% clinical trials · 2% reviews.
Co-invented the CAPP-Seq method for reading tumour DNA in blood and used it to track lymphoma and lung cancer.
Showed that colorectal cancers grow as a 'Big Bang' and that metastasis can be seeded years before diagnosis.
Crystal Mackall is a cell therapy pioneer whose team brought GD2 CAR-T to children with brain tumours that had no treatment.
In 1971 he put nearly all of his international holdings into a cancer research institute that carries his name reluctantly; it has since spent more than $1.8 billion of its own money on cancer science.
Heather Wakelee is a lung cancer leader who led the first adjuvant immunotherapy trial to change practice.
Isolated the first blood stem cells and discovered the 'don't eat me' signal CD47 on cancer cells.
Led the futibatinib trial and defined how FGFR2-driven bile duct cancers become resistant to targeted drugs.
Radiation oncologist who showed a blood test can detect leftover lung cancer months before scans.
Founded cancer neuroscience and led the GD2 CAR-T trial that produced the first regressions of diffuse midline glioma.
She and Mark Zuckerberg founded the Chan Zuckerberg Biohub with the stated mission to cure or prevent all disease; its programmes include engineering the immune system to detect cancer and other diseases early.
Chairs NRG Oncology, the largest US radiotherapy cooperative group, and leads head and neck de-escalation trials.
Developed the first antibody treatment for cancer, rituximab, and still works on training the immune system against lymphoma.
In May 2025 the Weill Family Foundation's $100 million challenge launched a $200 million, ten-year cancer research partnership between UCSF and Stanford, the two big Bay Area cancer centres that usually compete.
In 2016 he founded and funded an institute that runs cancer immunotherapy research as one network across a dozen leading cancer centres, sharing data, samples and patents rather than competing for them.
Steven Artandi is a telomerase biologist who directs Stanford's cancer institute.
Stanford dermatologist who led MAVORIC, the trial that established mogamulizumab for mycosis fungoides and Sézary syndrome after earlier treatment.
The driver count is a prognostic score in itself, and the allele matters: G12D is the pancreatic allele with the worst outlook and the one the new selective inhibitors chase.
This paper made AI-assisted skin cancer triage a serious clinical prospect and became the template for later work in radiology and pathology. Prospective trials, regulatory clearance and performance across skin tones followed, and are where its promise is now being tested.
The paper launched two decades of work on tumour-initiating cells in solid cancers, on why relapse follows apparently complete responses, and on measuring residual disease at the level of the cells that can regrow it. It also connected developmental biology pathways to cancer drug discovery.
Shares Emerson Collective, Priscilla Chan, Sanford I. Weill, Damon Runyon Cancer Research Foundation.
Shares Biology-guided radiotherapy (RefleXion X1, SCINTIX), CAR-T for glioma (IL13Rα2, GD2, EGFRvIII, multi-target), Parker Institute for Cancer Immunotherapy, The brain: barrier and sanctuary.
Shares Crystal L. Mackall, CAR-T for glioma (IL13Rα2, GD2, EGFRvIII, multi-target), Diffuse midline glioma, H3 K27-altered (including DIPG), The brain: barrier and sanctuary.
Shares Damon Runyon Cancer Research Foundation, Cut the nerve supply to tumours with old drugs, Daniel K. Ludwig, Ludwig Cancer Research.
Shares Irving L. Weissman, Reya 2001: stem cells, cancer and cancer stem cells, Hedgehog signalling, Cancer stem cells & phenotypic plasticity.
Shares Evo 2 (Arc Institute, NVIDIA), Chan Zuckerberg Biohub, Virtual cell roadmap: from bulk omics to a predictive model of a cancer cell.
Shares Emerson Collective, Priscilla Chan, Sanford I. Weill, Damon Runyon Cancer Research Foundation.
Shares Crystal L. Mackall, CAR-T for glioma (IL13Rα2, GD2, EGFRvIII, multi-target), Neuroblastoma (paediatric), CAR-T cell therapy.
Open-source projects that this organisation maintains, from OnCo's own catalogue: licence and last activity as the repository reported them on the day of the fetch. Listing is not endorsement; check the licence before reuse and the validation before clinical use.
Stanford's vision-language foundation model for abdominal CT trained with radiology reports and diagnosis codes.
Pathology Language-Image Pretraining: a CLIP-style model trained on pathology images from Twitter, with weights.
Stanford's foundation model that embeds any cell from any species into a shared space.
Stanford's vision-language foundation model for precision oncology trained on pathology images and text.
An open-hardware personal radiation dosimeter from Stanford, built from a low-cost scintillator and off-the-shelf parts.