{"entity":{"id":"stanford","kind":"institution","name":"Stanford Health Care / Stanford Cancer Institute","aka":[],"tldr":"Stanford is home to CAR-T innovation (Mackall, Majzner), the CD47 discovery (Weissman), and AI in medicine.","summary":"Stanford Health Care and the Stanford Cancer Institute in California hold NCI comprehensive designation and thirtieth place in the Newsweek/Statista oncology ranking, and they matter for CAR-T innovation, the CD47 discovery and AI in medicine. Crystal L. Mackall and Majzner developed GD2 CAR-T for diffuse intrinsic pontine glioma, Irving L. Weissman's CD47 work is the origin of magrolimab, Adler invented the CyberKnife, and Ronald Levy leads its lymphoma tradition, with Ash A. Alizadeh, Christina Curtis and Heather A. Wakelee also listed. OnCo links it to Evo 2, GenePT and the Merlin CT vision-language model, to pathways from chromosomal instability to ferroptosis, and to funders including the Chan Zuckerberg Biohub and the Parker Institute. Getting CAR-T past the blood-brain barrier durably is the bottleneck its glioma work confronts. Programmes and people are listed below.","asOf":"2026-09-04","links":[{"label":"Official website","url":"https://cancer.stanford.edu"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":["car-t","sbrt","cyberknife","radiosurgery-srs","biology-guided-radiotherapy"],"targets":["cd47"],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":["steven-artandi","crystal-mackall","irving-weissman","ronald-levy","heather-wakelee","ash-alizadeh","maximilian-diehn","lipika-goyal","michelle-monje","christina-curtis","quynh-thu-le"],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Stanford","country":"US","lat":37.434,"lng":-122.175,"institutionType":"university","website":"https://cancer.stanford.edu","nci":"comprehensive","newsweekOncology2026":30,"university":"Stanford University","programs":["CAR-T for paediatric brain tumours","AI in oncology","Lymphoma"]},"route":"/institutions/stanford/","neighbours":{"technology":[{"id":"biology-guided-radiotherapy","kind":"technology","name":"Biology-guided radiotherapy (RefleXion X1, SCINTIX)","route":"/technologies/biology-guided-radiotherapy/"},{"id":"car-t","kind":"technology","name":"CAR-T cell therapy","route":"/technologies/car-t/"},{"id":"glioma-car-t","kind":"technology","name":"CAR-T for glioma (IL13Rα2, GD2, EGFRvIII, multi-target)","route":"/technologies/glioma-car-t/"},{"id":"cyberknife","kind":"technology","name":"CyberKnife robotic radiosurgery","route":"/technologies/cyberknife/"},{"id":"evo2","kind":"technology","name":"Evo 2 (Arc Institute, NVIDIA)","route":"/technologies/evo2/"},{"id":"gears","kind":"technology","name":"GEARS and perturbation prediction benchmarks","route":"/technologies/gears/"},{"id":"genept","kind":"technology","name":"GenePT","route":"/technologies/genept/"},{"id":"merlin-ct","kind":"technology","name":"Merlin (Stanford abdominal CT vision-language model)","route":"/technologies/merlin-ct/"},{"id":"musk","kind":"technology","name":"MUSK (Stanford, vision-language pathology)","route":"/technologies/musk/"},{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"},{"id":"radiosurgery-srs","kind":"technology","name":"Stereotactic radiosurgery (Gamma Knife, CyberKnife, linac SRS)","route":"/technologies/radiosurgery-srs/"},{"id":"universal-cell-embedding","kind":"technology","name":"Universal Cell Embedding (UCE)","route":"/technologies/universal-cell-embedding/"}],"target":[{"id":"cd47","kind":"target","name":"CD47","route":"/targets/cd47/"}],"person":[{"id":"ash-alizadeh","kind":"person","name":"Ash A. Alizadeh","route":"/people/ash-alizadeh/"},{"id":"christina-curtis","kind":"person","name":"Christina Curtis","route":"/people/christina-curtis/"},{"id":"crystal-mackall","kind":"person","name":"Crystal L. Mackall","route":"/people/crystal-mackall/"},{"id":"daniel-ludwig","kind":"person","name":"Daniel K. Ludwig","route":"/people/daniel-ludwig/"},{"id":"heather-wakelee","kind":"person","name":"Heather A. Wakelee","route":"/people/heather-wakelee/"},{"id":"irving-weissman","kind":"person","name":"Irving L. Weissman","route":"/people/irving-weissman/"},{"id":"lipika-goyal","kind":"person","name":"Lipika Goyal","route":"/people/lipika-goyal/"},{"id":"maximilian-diehn","kind":"person","name":"Maximilian Diehn","route":"/people/maximilian-diehn/"},{"id":"michelle-monje","kind":"person","name":"Michelle Monje","route":"/people/michelle-monje/"},{"id":"priscilla-chan","kind":"person","name":"Priscilla Chan","route":"/people/priscilla-chan/"},{"id":"quynh-thu-le","kind":"person","name":"Quynh-Thu Le","route":"/people/quynh-thu-le/"},{"id":"ronald-levy","kind":"person","name":"Ronald Levy","route":"/people/ronald-levy/"},{"id":"sanford-weill","kind":"person","name":"Sanford I. Weill","route":"/people/sanford-weill/"},{"id":"sean-parker","kind":"person","name":"Sean Parker","route":"/people/sean-parker/"},{"id":"steven-artandi","kind":"person","name":"Steven E. Artandi","route":"/people/steven-artandi/"},{"id":"youn-kim","kind":"person","name":"Youn H. Kim","route":"/people/youn-kim/"}],"cancer":[{"id":"dipg-dmg","kind":"cancer","name":"Diffuse midline glioma, H3 K27-altered (including DIPG)","route":"/cancers/dipg-dmg/"},{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"},{"id":"neuroblastoma","kind":"cancer","name":"Neuroblastoma (paediatric)","route":"/cancers/neuroblastoma/"}],"paper":[{"id":"paper-qian-driver-genes-outcomes-resected-pancreatic-jama-oncol-2018","kind":"paper","name":"Association of alterations in main driver genes with outcomes of patients with resected pancreatic ductal adenocarcinoma","route":"/key-papers/paper-qian-driver-genes-outcomes-resected-pancreatic-jama-oncol-2018/"},{"id":"paper-esteva-skin-cancer-deep-learning-nature-2017","kind":"paper","name":"Esteva 2017: a deep neural network classifies skin cancer at dermatologist level","route":"/key-papers/paper-esteva-skin-cancer-deep-learning-nature-2017/"},{"id":"paper-reya-cancer-stem-cells-nature-2001","kind":"paper","name":"Reya 2001: stem cells, cancer and cancer stem cells","route":"/key-papers/paper-reya-cancer-stem-cells-nature-2001/"}],"institution":[{"id":"cz-biohub","kind":"institution","name":"Chan Zuckerberg Biohub","route":"/institutions/cz-biohub/"},{"id":"damon-runyon","kind":"institution","name":"Damon Runyon Cancer Research Foundation","route":"/institutions/damon-runyon/"},{"id":"emerson-collective","kind":"institution","name":"Emerson Collective","route":"/institutions/emerson-collective/"},{"id":"ludwig-cancer-research","kind":"institution","name":"Ludwig Cancer Research","route":"/institutions/ludwig-cancer-research/"},{"id":"nci","kind":"institution","name":"National Cancer Institute (NIH)","route":"/institutions/nci/"},{"id":"parker-institute","kind":"institution","name":"Parker Institute for Cancer Immunotherapy","route":"/institutions/parker-institute/"}],"bottleneck":[{"id":"b-brain-delivery","kind":"bottleneck","name":"The brain: barrier and sanctuary","route":"/bottlenecks/b-brain-delivery/"}],"idea":[{"id":"idea-ecdna-targeting","kind":"idea","name":"Attack extrachromosomal DNA, the engine of oncogene amplification","route":"/ideas/idea-ecdna-targeting/"},{"id":"idea-nerve-tumour-blockade","kind":"idea","name":"Cut the nerve supply to tumours with old drugs","route":"/ideas/idea-nerve-tumour-blockade/"},{"id":"idea-bio1-lytac-surface-degraders","kind":"idea","name":"Drag cancer's surface and secreted proteins to the cell's recycling bin","route":"/ideas/idea-bio1-lytac-surface-degraders/"},{"id":"idea-targeting-aneuploidy","kind":"idea","name":"Is aneuploidy itself a druggable vulnerability?","route":"/ideas/idea-targeting-aneuploidy/"},{"id":"idea-ferroptosis-persisters","kind":"idea","name":"Kill drug-tolerant persisters through ferroptosis","route":"/ideas/idea-ferroptosis-persisters/"}],"pathway":[{"id":"cancer-neuroscience","kind":"pathway","name":"Cancer neuroscience (nerve-tumour signalling)","route":"/pathways/cancer-neuroscience/"},{"id":"cancer-stem-cells-plasticity","kind":"pathway","name":"Cancer stem cells & phenotypic plasticity","route":"/pathways/cancer-stem-cells-plasticity/"},{"id":"chromosomal-instability","kind":"pathway","name":"Chromosomal instability & aneuploidy","route":"/pathways/chromosomal-instability/"},{"id":"ferroptosis-cell-death","kind":"pathway","name":"Ferroptosis & regulated cell death","route":"/pathways/ferroptosis-cell-death/"},{"id":"hedgehog","kind":"pathway","name":"Hedgehog signalling","route":"/pathways/hedgehog/"},{"id":"swi-snf-chromatin","kind":"pathway","name":"SWI/SNF chromatin remodelling","route":"/pathways/swi-snf-chromatin/"}],"roadmap":[{"id":"virtual-cell","kind":"roadmap","name":"Virtual cell roadmap: from bulk omics to a predictive model of a cancer cell","route":"/roadmaps/virtual-cell/"}]}}