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A single very high dose, or a few doses, aimed at a small brain or spine target with millimetre precision, replacing whole-brain radiotherapy for most brain metastases.
Lars Leksell treated the first patients with the Gamma Knife in 1968 using converging cobalt-60 beams; today the same idea is delivered by dedicated Gamma Knife units, the robotic CyberKnife and conventional linacs fitted with fine collimators and image guidance. Radiosurgery treats brain metastases, meningiomas, vestibular schwannomas, arteriovenous malformations and, increasingly, spinal metastases. Randomised trials showed that treating brain metastases with radiosurgery alone preserves memory and thinking better than adding whole-brain radiotherapy, with no loss of survival.
Many narrow beams converge on a small target so the dose falls off steeply within millimetres; rigid immobilisation and image guidance keep the target within the beam.
Query for this technology: (TITLE:"Stereotactic radiosurgery" OR ABSTRACT:"Stereotactic radiosurgery" OR TITLE:"Gamma Knife, CyberKnife, linac SRS" OR ABSTRACT:"Gamma Knife, CyberKnife, linac SRS") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Stereotactic radiosurgery (Gamma Knife, CyberKnife, linac SRS), not a curated reading list.
Shares Nordion (Sotera Health), Linac, proton system and brachytherapy machine manufacturing, Gamma Knife, IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares CyberKnife robotic radiosurgery, SBRT / SABR (stereotactic radiotherapy), IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares CyberKnife robotic radiosurgery, SBRT / SABR (stereotactic radiotherapy), Metastatic cancer (cancer that has spread) and the tag radiation-wave1.
Shares CyberKnife robotic radiosurgery, SBRT / SABR (stereotactic radiotherapy), IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares Palliation in lung cancer: breathlessness, pleural effusion, blocked airway, bone and brain, Extensive-stage small-cell lung cancer, SBRT / SABR (stereotactic radiotherapy), IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares Patient positioning and surface guidance systems (AlignRT, Catalyst, ExacTrac Dynamic), IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares SBRT / SABR (stereotactic radiotherapy), IMRT / IGRT (modern external beam) and the tag radiation-wave1.
Shares Lung cancer (all types), IMRT / IGRT (modern external beam) and the tag radiation-wave1.