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Sunnybrook Odette Cancer Centre
One of Canada's largest cancer centres, where focused ultrasound first opened the blood-brain barrier in a patient and Canada's first MR-linac was installed.
Also called: Odette Cancer CentreSunnybrook Health Sciences Centre
Overview
The Odette Cancer Centre at Sunnybrook Health Sciences Centre is one of Canada's largest cancer programmes and a University of Toronto teaching site. Sunnybrook Research Institute's Kullervo Hynynen pioneered MR-guided focused ultrasound, and in 2015 neurosurgeon Todd Mainprize used it to open the blood-brain barrier non-invasively in a brain tumour patient for the first time, work now in trials for glioblastoma and brain metastases with Insightec. Radiation oncology is a signature strength: Arjun Sahgal led the CCTG SC.24 trial of stereotactic radiotherapy for spinal metastases, Gregory Czarnota develops ultrasound-stimulated microbubble radiosensitisation, and Sunnybrook installed Canada's first MR-linac. The Odette Breast Centre and a large GU programme (including prostate brachytherapy) complete the picture.
Location
Toronto, ON, CA
Type
cancer center · University of Toronto
Newsweek 2026 oncology rank
Not in top 300 listing used
OnCo score
#109 · 38 points (0 Newsweek + 0 NCI + 38 from 19 linked objects) · ranking
- Focused ultrasound and blood-brain barrier opening
- MR-linac and stereotactic radiotherapy
- Breast cancer
- Genitourinary oncology
Monika Krzyzanowska
Chief, Odette Cancer Program, Sunnybrook Health Sciences Centre
Medical oncologyHealth services researchQuality of cancer care
Medical oncologist and health services researcher who leads the Odette Cancer Program at Sunnybrook in Toronto, one of Canada's largest cancer centres.
Simron Singh
Medical Oncologist and Co-Director, Susan Leslie Clinic for Neuroendocrine Tumours, Sunnybrook Odette Cancer Centre
Neuroendocrine tumoursRadioligand therapyHealth services research
Led NETTER-2, which moved lutetium dotatate into first-line treatment of higher-grade neuroendocrine tumours.
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BrachytherapyFocused ultrasound & histotripsyFocused-ultrasound blood-brain barrier openingGamma KnifeMR-guided adaptive radiotherapySBRT / SABR (stereotactic radiotherapy)Stereotactic radiosurgery (Gamma Knife, CyberKnife, linac SRS)Transcranial focused ultrasound systems (Exablate Neuro, SonoCloud)