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Cancer that has spread to only a few places, which may still be curable by treating each spot.
Oligometastatic disease is cancer that has spread to only a few sites, usually no more than three to five metastases, and may still be curable if each spot is treated. The SABR-COMET trial supported metastasis-directed SBRT / SABR (stereotactic radiotherapy), and the ESTRO/EORTC classification distinguishes synchronous, oligorecurrent and oligoprogressive disease, the last covered by the related term Oligoprogression. PSMA PET has expanded detection of this state in Prostate cancer, and the term is also referenced by the Renal cell carcinoma entry and the bottleneck on metastasis biology. Ideas building on it include PSMA-PET-guided metastasis-directed therapy as a curative strategy and a test to tell true oligometastatic disease from hidden widespread spread.
Showing the technology this term belongs to: SBRT / SABR (stereotactic radiotherapy).
One term page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
Metastatic prostate cancer is a communicating population, not a set of independent colonies, which is an argument for treating the whole body rather than chasing individual deposits, and an argument that resistance to androgen receptor drugs will emerge in several places at once because it emerges convergently.
Shares ORIOLE, STOMP, PSMA PET, SBRT / SABR (stereotactic radiotherapy).
Shares ORIOLE, STOMP, SBRT / SABR (stereotactic radiotherapy), Metastatic cancer (cancer that has spread).
Shares PSMA-PET-guided metastasis-directed therapy as a curative strategy in oligorecurrent prostate cancer, ORIOLE, STOMP, When the blood test is positive, hunt for the lesion with sensitive imaging.
Shares Stereotactic body radiotherapy (SBRT / SABR), The evolutionary history of lethal metastatic prostate cancer, Renal cell carcinoma, Metastatic cancer (cancer that has spread).
Shares CLOCC, EORTC 40983, New EPOC, CAIRO5.
Shares Hallmark: activating invasion and metastasis, Metastasis, Organ tropism: seed and soil, The metastatic cascade.
Shares Systemic versus local therapy, Metastasis, The metastatic cascade.
Shares Hallmark: activating invasion and metastasis, Metastasis, The metastatic cascade.