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Whether the goal of treatment is to eliminate the cancer for good (curative) or to control it, relieve symptoms and extend life when cure is not possible (palliative). The intent, not the drug, defines the word: the same chemotherapy can be either.
Curative-intent treatment usually combines surgery or radiotherapy with systemic therapy for localised or locally advanced disease and accepts more toxicity for a chance of cure; palliative-intent treatment for metastatic disease balances life extension against quality of life, and includes palliative radiotherapy for pain or bleeding and palliative surgery for obstruction. Best supportive care means symptom management without anticancer treatment and is the comparator in some trials. A growing minority of metastatic settings (oligometastatic disease, germ cell tumours, some lymphomas, MSI-high colorectal cancer on immunotherapy) blur the line, and early palliative care alongside curative or life-prolonging treatment improves outcomes.
Showing the technology this term belongs to: Early integrated palliative care.
Shares SPCG-7/SFUO-3, ASCENDE-RT, EORTC 22991, RTOG 94-08.
Shares Current treatment options in oncology, Current oncology reports, Japanese journal of clinical oncology, Palliative radiotherapy.
Shares RTOG 94-08, EORTC 22961, EORTC 22863, DART 01/05 GICOR.
Shares PROFIT (Prostate Fractionated Irradiation Trial), RTOG 94-08, RTOG 0415, How many radiotherapy visits: the prostate fractionation trials.
Shares SPCG-7/SFUO-3, RTOG 94-08, EORTC 22961, EORTC 22863.
Shares PROFIT (Prostate Fractionated Irradiation Trial), RTOG 0415, How many radiotherapy visits: the prostate fractionation trials, Prostate cancer.
Shares ASCENDE-RT, EORTC 22991, PROFIT (Prostate Fractionated Irradiation Trial), RTOG 94-08.
Shares SPCG-7/SFUO-3, ASCENDE-RT, EORTC 22991, SPCG-4 (Scandinavian Prostate Cancer Group Study 4).