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Short courses of radiation, often a single treatment, to relieve pain from bone metastases, stop bleeding, open blocked airways or protect the spinal cord. Among the most cost-effective treatments in cancer.
About 40% of radiotherapy courses are palliative. Trials established that a single 8 Gy fraction equals multi-fraction regimens for uncomplicated bone metastases (RTOG 9701, Dutch Bone Metastasis Study; ~60% pain response), that 8 Gy ×1 or 20 Gy ×5 suffices for spinal cord compression in poor-prognosis patients (SCORAD III, ICORG), and that whole-brain radiotherapy adds little for poor-performance NSCLC brain metastases (QUARTZ) while SRS replaces it for limited metastases. Other indications: haemostasis (bladder, gynaecologic, lung), airway and oesophageal obstruction, SVC syndrome, hepatic pain, skin fungation. Underuse of single fractions persists in fee-for-service systems; rapid-access palliative clinics shorten time to treatment.
Deliver a biologically sufficient dose for symptom control with minimum visits and toxicity, using simple techniques (parallel-opposed or 3D) or SBRT where oligometastatic ablation is intended.
One technology page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
One technology page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
Query for this technology: (TITLE:"Palliative radiotherapy" OR ABSTRACT:"Palliative radiotherapy") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Palliative radiotherapy, not a curated reading list.
Shares Pain with gallbladder and bile duct cancer, Palliation in colorectal cancer: obstruction, stents, stomas and liver capsule pain, QUARTZ, Anaplastic thyroid cancer and the tag supportive.
Shares Palliation in lung cancer: breathlessness, pleural effusion, blocked airway, bone and brain, Bone-modifying agents (bisphosphonates, denosumab), Bone metastases and skeletal-related events, Multiple myeloma and the tag supportive.
Shares Relapsed and refractory classical Hodgkin lymphoma, Mantle cell lymphoma, Small-cell lung cancer, Lung cancer (all types) and the tag supportive.
Shares Relapsed and refractory classical Hodgkin lymphoma, Mantle cell lymphoma, Lung cancer (all types), Diffuse large B-cell lymphoma and the tag supportive.
Shares Cancer pain management, Curative intent vs palliative intent and the tag supportive.
Shares Relapsed and refractory classical Hodgkin lymphoma, Mantle cell lymphoma, Small-cell lung cancer, Lung cancer (all types) and the tag supportive.
Shares Bone-modifying agents (bisphosphonates, denosumab), HR-positive / HER2-negative breast cancer and the tag supportive.
Shares Mantle cell lymphoma, Multiple myeloma, Diffuse large B-cell lymphoma and the tag supportive.