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Systematic treatment of cancer pain with opioids, adjuvant drugs, radiation and procedures such as nerve blocks and intrathecal pumps. Most pain can be controlled, yet under-treatment remains common, especially where opioids are unavailable.
Pain affects ~55% of patients during treatment and ~66% with advanced disease. The WHO analgesic ladder (1986) established oral morphine as the core; modern practice adds mechanism-based adjuvants (dexamethasone, gabapentinoids, duloxetine for chemotherapy-induced neuropathy per CALGB 170601, ketamine, cannabinoids with weak evidence), bone-directed therapy (single-fraction radiotherapy, bisphosphonates/denosumab, radiopharmaceuticals), interventional procedures (coeliac plexus neurolysis for pancreatic cancer, vertebroplasty, intrathecal drug delivery, cordotomy), and non-pharmacologic approaches. Opioid stewardship balances the US overdose epidemic (which reduced cancer patients' access) against the ~80% of the world's population with essentially no morphine access. Cancer survivors with chronic pain need distinct guidance (ASCO 2016).
Assess pain type (nociceptive, neuropathic, bone, visceral) and intensity; treat cause (radiation, surgery, systemic therapy) and symptom in parallel with a stepped, mechanism-based regimen and regular reassessment.
These are fast-acting forms of the opioid fentanyl, taken as a tablet against the cheek or as a nasal spray, for sudden flares of pain in people whose cancer pain is otherwise controlled by a regular opioid. They are only for patients already tolerant to opioids.
Methylnaltrexone (Relistor) is an injection or tablet that relieves the severe constipation caused by strong painkillers in people with advanced cancer, without blocking the pain relief itself.
Query for this technology: (TITLE:"Cancer pain management" OR ABSTRACT:"Cancer pain management") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Cancer pain management, not a curated reading list.
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Shares Clinical hypnosis for procedures, pain and hot flushes, Evidence-based integrative oncology, Supportive care and survivorship roadmap: making treatment bearable → proving it extends life → caring for tens of millions afterwards, Early integrated palliative care and the tag supportive.
Shares Supportive care and survivorship roadmap: making treatment bearable → proving it extends life → caring for tens of millions afterwards, Gallbladder cancer, Small-cell lung cancer, Lung cancer (all types) and the tag supportive.
Shares Bone-modifying agents (bisphosphonates, denosumab), Lung cancer (all types), Prostate cancer, Non-small-cell lung cancer and the tag supportive.
Shares Supportive care and survivorship roadmap: making treatment bearable → proving it extends life → caring for tens of millions afterwards, Lung cancer (all types), Breast cancer (all types), Pancreatic ductal adenocarcinoma and the tag supportive.
Shares Supportive care and survivorship roadmap: making treatment bearable → proving it extends life → caring for tens of millions afterwards, Pancreatic ductal adenocarcinoma, Non-small-cell lung cancer and the tag supportive.
Shares Early integrated palliative care, Non-small-cell lung cancer and the tag supportive.
Shares Bone-modifying agents (bisphosphonates, denosumab) and the tag supportive.