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Sorrento Therapeutics
Sorrento was a San Diego biotech with a sprawling pipeline of antibodies, cell therapies and a resiniferatoxin pain programme for cancer pain; it filed for bankruptcy in 2023.
Also called: Sorrento Therapeutics, Inc.Sorrento
Overview
Sorrento Therapeutics, founded in 2006 in San Diego, built a broad portfolio spanning antibody libraries, CAR-T and dimeric antigen receptor cell therapies, a Cynviloq paclitaxel formulation and resiniferatoxin for intractable cancer pain, several of which reached phase 3. The company filed for Chapter 11 bankruptcy in 2023 and its assets were sold. Its trials remain on ClinicalTrials.gov under Sorrento as lead sponsor. Its registered cancer trials include the CD38-directed antibody-drug conjugate STI-6129 in multiple myeloma (NCT05308225), anti-CEA CAR-T cells in pancreatic cancer with liver metastases (NCT04037241), abivertinib with abiraterone in prostate cancer (NCT05361915) and resiniferatoxin for intractable cancer pain (NCT04572776).
Headquarters
San Diego, CA, US
Scorecard
All companies#431of 1244 companies, score 8
- phase 1/2 +1
- targets +2
- modalities +2
- registry trials +3
0 approved, 0 in phase 3, 1 earlier, 1 targets, 3 registry studies. Formula on the scorecards page.
Type
Stage
Wound down
Website
Founded
2006
Phase 2ADC
STI-6129 is an experimental antibody-drug conjugate from Zhejiang ACEA Pharmaceutical in phase 2 trials for multiple myeloma, aimed at CD38.
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