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Whether a cancer is caused by human papillomavirus. HPV-positive throat cancers are a different, far more curable disease than smoking-related ones, and the virus's DNA in blood can track the cancer.
Persistent high-risk HPV (types 16 and 18 mainly) causes virtually all cervical cancer and rising shares of oropharyngeal, anal, vulval and penile cancers; p16 immunohistochemistry is the surrogate marker in the oropharynx. HPV-positive oropharyngeal cancer has 3-year survival above 80% and its own AJCC staging, so trials test de-escalating radiotherapy dose or omitting chemotherapy, none of which has yet succeeded in a randomised trial. Circulating HPV DNA (ctHPV) detects recurrence months before imaging. HPV vaccination and HPV-based cervical screening are the route to eliminating cervical cancer.
Showing the technology this term belongs to: HPV & HBV vaccination.
Shares Visual inspection with acetic acid (VIA) for cervical screening, Vaginal adenocarcinoma (including DES-associated clear cell adenocarcinoma), Early cervical cancer and fertility-sparing surgery, Vaginal squamous cell carcinoma (HPV-associated).
Shares Anal high-grade squamous intraepithelial lesions (precursor), Visual inspection with acetic acid (VIA) for cervical screening, Vaginal squamous cell carcinoma (HPV-associated), Vaginal cancer.
Shares Anal high-grade squamous intraepithelial lesions (precursor), Localised penile cancer (organ-confined, node-negative), Node-positive and metastatic penile cancer, Vaginal squamous cell carcinoma (HPV-associated).
Shares Anal high-grade squamous intraepithelial lesions (precursor), Localised penile cancer (organ-confined, node-negative), Vaginal squamous cell carcinoma (HPV-associated), Penile cancer.
Shares Vaginal squamous cell carcinoma (HPV-associated), Vaginal cancer, HPV & HBV vaccination, Cervical cancer.
Shares Anal high-grade squamous intraepithelial lesions (precursor), Localised penile cancer (organ-confined, node-negative), Vaginal squamous cell carcinoma (HPV-associated), Vaginal cancer.
Shares Localised penile cancer (organ-confined, node-negative), Penile cancer, HPV & HBV vaccination.
Shares Vaginal squamous cell carcinoma (HPV-associated), Vaginal cancer, Cervical cancer.