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Destroying precancerous cervical cells with a heated or frozen probe in under a minute, the tool that makes screen-and-treat possible where there are no surgeons.
WHO (2019) recommends thermal ablation (100°C probe, 20-40 seconds) or cryotherapy for eligible CIN2+ lesions in screen-and-treat programmes, often after visual inspection with acetic acid (VIA) or HPV testing. Portable battery-powered devices cost a few hundred dollars; cure rates ~85-95% for eligible lesions. Central to the WHO cervical cancer elimination strategy's 90% treatment target.
Coagulative necrosis (thermal) or freeze-thaw injury (cryo) of the cervical transformation zone.
Aminolevulinic acid is painted on sun-damaged skin and then activated with a lamp, destroying actinic keratoses before they can become skin cancer; in Europe the gel is also approved for superficial basal cell carcinoma.
Query for this technology: (TITLE:"Thermal ablation and cryotherapy for cervical precancer" OR ABSTRACT:"Thermal ablation and cryotherapy for cervical precancer") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Thermal ablation and cryotherapy for cervical precancer, not a curated reading list.
Shares Single-dose HPV vaccination plus HPV self-sampling to reach WHO elimination in low-income countries, Anal high-grade squamous intraepithelial lesions (precursor), Localised penile cancer (organ-confined, node-negative), HPV-associated vulvar squamous cell carcinoma.
Shares Anal high-grade squamous intraepithelial lesions (precursor), Localised penile cancer (organ-confined, node-negative), HPV-independent vulvar squamous cell carcinoma (p53-mutant), HPV-associated vulvar squamous cell carcinoma.
Shares Cervical precancer (CIN, HSIL/LSIL), Basement membrane & tissue barriers, Vaginal squamous cell carcinoma (HPV-associated), Vaginal cancer.
Shares Single-dose HPV vaccination plus HPV self-sampling to reach WHO elimination in low-income countries, Cancer prevention roadmap: tobacco control and vaccines → biomarker-guided chemoprevention → interception in carriers, Global access and affordability roadmap: essential medicines and generics → biosimilars and frugal trials → reliance, pooling and homegrown innovation, Prevention we already have is not deployed.
Shares Anal high-grade squamous intraepithelial lesions (precursor), Localised penile cancer (organ-confined, node-negative), Vaginal squamous cell carcinoma (HPV-associated), Vaginal cancer.
Shares Cervical precancer (CIN, HSIL/LSIL), HPV DNA testing and self-sampling, Prevention we already have is not deployed, Cervical cancer.
Shares HPV DNA testing and self-sampling, Cancer prevention roadmap: tobacco control and vaccines → biomarker-guided chemoprevention → interception in carriers, Global access and affordability roadmap: essential medicines and generics → biosimilars and frugal trials → reliance, pooling and homegrown innovation, Prevention we already have is not deployed.
Shares Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants, Global access and affordability roadmap: essential medicines and generics → biosimilars and frugal trials → reliance, pooling and homegrown innovation, Prevention we already have is not deployed, Most of the world has almost no cancer care.