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Thermal ablation kills a tumour with heat or cold delivered through a needle, with no incision required.
Thermal ablation destroys a tumour through a percutaneous probe that delivers radiofrequency current, microwave energy, or argon-based freezing, causing coagulative necrosis or ice-ball cell death without an incision. Radiofrequency and microwave ablation are curative-intent options for small HCC, liver metastases, lung, and kidney tumours; cryoablation is used for kidney, bone, and (in trials) small breast cancers. Procedures are image-guided by CT or ultrasound, done as outpatients, repeatable, and preserve organ function. Combination with immunotherapy exploits the antigen release from dying tumour cells, though the clinical value of that is still being tested. Limits are a size ceiling of around 3 cm and the heat-sink effect near large vessels, which can leave viable cells. The simple version is that a needle kills the tumour with heat or cold.
Percutaneous probe delivers RF current, microwave energy, or argon-based freezing; coagulative necrosis or ice-ball cell death.
Query for this technology: (TITLE:"radiofrequency ablation" OR ABSTRACT:"radiofrequency ablation" OR TITLE:"microwave ablation" OR ABSTRACT:"microwave ablation" OR TITLE:"cryoablation" OR ABSTRACT:"cryoablation") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Thermal ablation (RFA, microwave, cryo), not a curated reading list.
Shares Photothermal (plasmonic) nanoparticle ablation, Histotripsy as an immune primer, Mechanically pulverise one tumour with ultrasound to wake the immune system, In situ vaccination.
Shares Boston Scientific, BCLC staging, Liver-directed therapy (TACE, TARE, HAI, ablation), Grade 3 well-differentiated neuroendocrine tumour.
Shares AngioDynamics, Mechanically pulverise one tumour with ultrasound to wake the immune system, Device-agnostic public trials of ablation technologies against surgery, Cryoablation systems.
Shares Monteris Medical, Quantum Surgical, XACT Robotics, Partial nephrectomy, ablation & active surveillance of small renal masses.
Shares Histotripsy as an immune primer, Mechanically pulverise one tumour with ultrasound to wake the immune system, Device-agnostic public trials of ablation technologies against surgery, Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants.
Shares Boston Scientific, Early hepatocellular carcinoma (BCLC 0 and A), Small intestinal neuroendocrine tumours, Surgery roadmap: radical operations → less surgery → no surgery when a drug has done the work.
Shares Chromophobe renal cell carcinoma, Advanced and metastatic adrenocortical carcinoma (ENSAT stage IV or unresectable), Papillary renal cell carcinoma, Metastatic pheochromocytoma and paraganglioma.
Shares Chromophobe renal cell carcinoma, Imatinib-resistant GIST, Grade 3 well-differentiated neuroendocrine tumour, Papillary renal cell carcinoma.