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Gold nanoshells that accumulate in a tumour and cook it when a near-infrared laser is shone on them.
AuroLase uses silica-gold nanoshells that convert near-infrared light into heat. Nanospectra ran focal prostate ablation studies with MRI/ultrasound fusion guidance (NCT02680535, completed; extension NCT04240639, status unknown) and a lung study that was terminated. Published prostate cohorts reported ablation of the treated zone with preserved urinary and sexual function, but the technology has never been compared with established focal therapy in a randomised trial.
Nanoparticles tuned to absorb 800 nm light accumulate in tumour vasculature; laser illumination raises local temperature above the ablation threshold while surrounding tissue, lacking particles, is spared.
Query for this technology: (TITLE:"Photothermal plasmonic nanoparticle ablation" OR ABSTRACT:"Photothermal plasmonic nanoparticle ablation") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Photothermal (plasmonic) nanoparticle ablation, not a curated reading list.
Shares Radical oncology: what could change the war by 2035, Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants, Thermal ablation (RFA, microwave, cryo), Prostate cancer and the tag frontier.
Shares Optical & fluorescence imaging, Radical oncology: what could change the war by 2035 and the tag frontier.
Shares Radical oncology: what could change the war by 2035 and the tag frontier.
Shares Radical oncology: what could change the war by 2035 and the tag frontier.
Shares Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants and the tag frontier.
Shares Radical oncology: what could change the war by 2035 and the tag frontier.
Shares Radical oncology: what could change the war by 2035 and the tag frontier.
Shares Radical oncology: what could change the war by 2035 and the tag frontier.