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Smelling cancer: measuring the trace chemicals a tumour puts into exhaled breath.
Tumour metabolism alters volatile organic compounds in breath, measurable by mass spectrometry or an electronic nose. Studies recruiting in 2026 include COBRA2 in colorectal cancer at Imperial College (NCT05844514), an e-nose response-monitoring study at Memorial Sloan Kettering (NCT06037941), and a breast cancer study by Breathe BioMedical (NCT06512350). Reported accuracies vary widely between cohorts and no breath test is approved for screening.
Breath is collected on a sorbent tube or sampled directly; gas chromatography-mass spectrometry or sensor arrays produce a pattern that machine learning classifies.
Query for this technology: (TITLE:"Breath and volatile-organic-compound detection" OR ABSTRACT:"Breath and volatile-organic-compound detection") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Breath and volatile-organic-compound detection, not a curated reading list.
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Shares Radical oncology: what could change the war by 2035 and the tag frontier.
Shares Radical oncology: what could change the war by 2035 and the tag frontier.