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Laser interstitial thermal therapy guides a laser fibre through a small skull hole, monitored by real-time MRI, to heat and destroy deep brain tumours a surgeon could not safely reach.
MRI thermometry-guided ablation (NeuroBlate, Visualase) for deep-seated or recurrent gliomas, radiation necrosis, and brain metastases. Case series suggest survival comparable to resection for selected recurrent glioblastoma; may transiently open the blood-brain barrier, enabling drug delivery (LAANTERN registry, phase 2 combinations with immunotherapy). No randomised evidence yet.
Stereotactically placed laser fibre delivers thermal energy; MR thermometry maps the ablation zone in real time.
Query for this technology: (TITLE:"Laser interstitial thermal therapy" OR ABSTRACT:"Laser interstitial thermal therapy" OR TITLE:"LITT" OR ABSTRACT:"LITT") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Laser interstitial thermal therapy (LITT), not a curated reading list.
Shares Laser interstitial thermal therapy systems (NeuroBlate, Visualase), Thermal ablation (RFA, microwave, cryo), MRI, Glioma & glioblastoma.
Shares Intraoperative MRI and CT, Laser interstitial thermal therapy systems (NeuroBlate, Visualase), Thermal ablation (RFA, microwave, cryo).
Shares Blood-brain barrier (BBB), The brain: barrier and sanctuary, Glioma & glioblastoma.
Shares Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants, MRI, Glioma & glioblastoma.
Shares Blood-brain barrier (BBB), The blood-brain barrier & brain metastasis, Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants, The brain: barrier and sanctuary.
Shares Laser interstitial thermal therapy systems (NeuroBlate, Visualase), MRI, Glioma & glioblastoma.
Shares Blood-brain barrier (BBB), The brain: barrier and sanctuary, Glioma & glioblastoma.
Shares Laser interstitial thermal therapy systems (NeuroBlate, Visualase), Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants.