The Jackson Laboratory in Maine breeds the world's genetically defined laboratory mice, including the immunodeficient NSG strain behind patient-derived xenograft research, and has held NCI basic cancer centre status since 1983; its PDX repository is open to academic and industry researchers.
Founded in 1929 by Clarence Cook Little, The Jackson Laboratory is the world's principal source of genetically defined laboratory mice, including the immunodeficient NSG strain that underpins patient-derived xenograft research, and has held NCI basic laboratory designation since 1983. Its cancer centre studies cancer genetics and genomics, the tumour microenvironment and drug response using mouse and PDX resources, with a large PDX repository available to academic and industry researchers. JAX Genomic Medicine in Farmington, Connecticut, extends the institute into human genomics and computational biology, and the Mouse Genome Informatics database is a core community resource.
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-15.
Matched to The JAX Cancer Center, including child institutions. 1 works · 0 citations · 100% open access · 0% clinical trials · 0% reviews.
| Work | Journal | Year | Citations |
|---|---|---|---|
| Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression | Research Square | 2024 | 0 |
Shares Patient-derived xenografts, Preclinical results do not reproduce, Lab models that fail to predict what happens in patients, National Cancer Institute (NIH).
Shares Patient-derived xenografts, Preclinical results do not reproduce, Lab models that fail to predict what happens in patients.
Shares Patient-derived xenografts, CRISPR functional genomics, Lab models that fail to predict what happens in patients.
Shares Preclinical results do not reproduce, Lab models that fail to predict what happens in patients, National Cancer Institute (NIH).
Shares Patient-derived xenografts, CRISPR functional genomics, Lab models that fail to predict what happens in patients.
Shares Preclinical results do not reproduce, Lab models that fail to predict what happens in patients, National Cancer Institute (NIH).
Shares Patient-derived xenografts, Preclinical results do not reproduce, Lab models that fail to predict what happens in patients.
Shares Preclinical results do not reproduce, Lab models that fail to predict what happens in patients.