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Failed laboratory experiments are rarely published, so other teams repeat them. A searchable place to deposit them would save years of duplicated work.
A structured repository for negative or null preclinical results, with a minimal reporting template (model, agent, dose, endpoint, effect size, confidence interval), digital object identifiers so deposits are citable, and funder credit for deposition. Existing journals for negative results have failed because they carry no career value; funder mandates and citable deposits change that calculus.
Shares Preclinical results do not reproduce, Lab models that fail to predict what happens in patients, Failures are hidden, Cancer Research UK.
Shares Estimation of clinical trial success rates and related parameters, Preclinical results do not reproduce, Lab models that fail to predict what happens in patients, Cancer Research UK.
Shares Preclinical results do not reproduce, Lab models that fail to predict what happens in patients.
Shares Preclinical results do not reproduce, Cancer Research UK, National Cancer Institute (NIH).
Shares Estimation of clinical trial success rates and related parameters, Preclinical results do not reproduce, Lab models that fail to predict what happens in patients.
Shares Preclinical results do not reproduce, Lab models that fail to predict what happens in patients.
Shares Failures are hidden, Cancer Research UK, National Cancer Institute (NIH).
Shares Estimation of clinical trial success rates and related parameters, Preclinical results do not reproduce, Lab models that fail to predict what happens in patients.