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FGFR1OP2 (FGFR1 oncogene partner 2) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role. Tied to Leukaemia.
May be involved in wound healing pathway.
Open Targets scores its association with cancer at 0.60 (direct and indirect evidence; datatypes literature 0.22, affected pathway 0.95, animal model 0.56, genetic association 0.03).
In plain words · FGFR1OP2 (FGFR1 oncogene partner 2) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role. Tied to Leukaemia.
FGFR1OP2 (FGFR1 oncogene partner 2) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role. Tied to Leukaemia.
May be involved in wound healing pathway. Location: Cytoplasm (UniProt).
No product in this corpus aims at FGFR1OP2 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 2000. Earliest sequence paper UniProt cites for the protein: Zhang Q.-H. et al, Genome Res, 2000, "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Source.
Sources: HGNC HGNC:23098 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q9NVK5 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000111790 (association with cancer (MONDO_0004992) 0.60; per-cancer scores at or above 0.5: leukaemia 0.55 (GraphQL API, CC0))
May be involved in wound healing pathway. Location: Cytoplasm (UniProt). Locus 12p11.23 (HGNC).
Query for this target: (TITLE:"FGFR1OP2" OR ABSTRACT:"FGFR1OP2" OR TITLE:"FGFR1 oncogene partner 2" OR ABSTRACT:"FGFR1 oncogene partner 2" OR TITLE:"DKFZp564O1863" OR ABSTRACT:"DKFZp564O1863") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about FGFR1OP2, not a curated reading list.