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ACOXL (Acyl-coenzyme A oxidase-like protein) is an enzyme. In the public catalogues the evidence so far is association rather than a proven role. Tied to Leukaemia.
UniProt has no function text for Q9NUZ1; HGNC names it "acyl-CoA oxidase like".
In plain words · ACOXL (Acyl-coenzyme A oxidase-like protein) is an enzyme. In the public catalogues the evidence so far is association rather than a proven role. Tied to Leukaemia.
ACOXL (Acyl-coenzyme A oxidase-like protein) is an enzyme. In the public catalogues the evidence so far is association rather than a proven role. Tied to Leukaemia.
UniProt has no function text for Q9NUZ1; HGNC names it "acyl-CoA oxidase like". Locus 2q13 (HGNC).
No product in this corpus aims at ACOXL yet. Inhibitors are shaped to fit the enzyme's active site so the reaction the cancer relies on stops.
First described 2004. Earliest sequence paper UniProt cites for the protein: Genome Res, 2004, "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Source.
Sources: HGNC HGNC:25621 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q9NUZ1 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000153093 (per-cancer scores at or above 0.5: leukaemia 0.51 (GraphQL API, CC0))
UniProt has no function text for Q9NUZ1; HGNC names it "acyl-CoA oxidase like". Locus 2q13 (HGNC).
Query for this target: (TITLE:"ACOXL" OR ABSTRACT:"ACOXL" OR TITLE:"acyl-CoA oxidase like" OR ABSTRACT:"acyl-CoA oxidase like" OR TITLE:"Acyl-coenzyme A oxidase-like protein" OR ABSTRACT:"Acyl-coenzyme A oxidase-like protein" OR TITLE:"FLJ11042" OR ABSTRACT:"FLJ11042" OR TITLE:"ACOX4" OR ABSTRACT:"ACOX4") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about ACOXL, not a curated reading list.