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institutionsInstitution
The Wistar Institute
America's first independent biomedical research institute (1892), an NCI basic cancer centre known for melanoma biology, monoclonal antibodies and DNA vaccines.
Also called: Wistar Institute Cancer Center
Overview
The Wistar Institute, founded in 1892 on the University of Pennsylvania campus, has held NCI basic laboratory designation since 1972. Hilary Koprowski and Zenon Steplewski's 17-1A antibody (edrecolomab) was among the first monoclonal antibodies tested in cancer patients; Meenhard Herlyn built one of the world's leading melanoma biology programmes and 3D skin and tumour models; David Weiner pioneered DNA vaccines, including candidates for glioblastoma; Rugang Zhang identified the ARID1A-EZH2 synthetic lethality in ovarian clear-cell carcinoma. President Dario Altieri studies survivin and mitochondrial signalling. Wistar has no clinic and translates through Penn, Jefferson, Fox Chase and industry partners.
Location
Philadelphia, PA, US
Type
research institute
Website
Newsweek 2026 oncology rank
Not in top 300 listing used
NCI designation
basic
OnCo score
#187 · 30 points (0 Newsweek + 8 NCI + 22 from 11 linked objects) · ranking
Research output
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-17.
Matched to The Wistar Institute, including child institutions. 287 works · 3,352 citations · 69% open access · 7% clinical trials · 2% reviews.
Oncology works per year
552022
582023
492024
662025
592026
Most works
- Paul M. Lieberman35 works
- Samantha S. Soldan23 works
- Italo Tempera20 works
- Andrew V. Kossenkov20 works
- Meenhard Herlyn18 works
- Maureen E. Murphy17 works
- Davide Maestri13 works
- David B. Weiner12 works
- Joel Cassel11 works
- Oluwadamilola M. Fayanju11 works
Most cited
- Melanoma biology
- Immunotherapy and vaccines
- Ovarian cancer epigenetics
- Antibody engineering
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