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Lonza
Lonza is the largest contract manufacturer for biologics, ADCs, and cell therapies, and owns the Synaffix ADC linker technology and the Cocoon cell-manufacturing platform.
Overview
Lonza, based in Basel and listed as LONN.SW, is the largest contract manufacturer for biologics, antibody-drug conjugates and cell therapies, and it owns the Synaffix ADC linker technology and the Cocoon cell-manufacturing platform. It is a Swiss CDMO with bioconjugation capacity in Visp, mammalian manufacturing worldwide including the former Genentech Vacaville site acquired in 2024, cell and gene therapy sites in Houston and Geleen, and the Cocoon closed platform. OnCo links it to ADC bioconjugation, closed automated cell-therapy manufacturing, viral vector manufacturing, sterile fill-finish and payload-linker synthesis, to Synaffix, and to the CDMO term. Whether contract manufacturing capacity, rather than science, becomes the limiting factor for ADCs and cell therapies is the question its position raises. Synaffix has its own page.
Headquarters
Basel, CH
Manufacturing
Capacity map- Lonza Visp Visp, CHADC conjugation, Payload and linker chemistry, Antibody drug substance
Type
Services · LONN.SW
Stage
Public
Website
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fronts
technologies
ADC bioconjugation manufacturing (CDMOs)Antibody manufacturing (CHO bioprocessing)Autologous CAR-T manufacturing, batch by batchClosed automated cell-therapy manufacturingDownstream purification (Protein A capture, viral clearance, polishing)GMP, inspections, Form 483s and warning lettersmRNA and lipid nanoparticle manufacturingPayload-linker synthesis (high-potency API)Small-molecule API synthesisSterile fill-finish and lyophilisationThe ADC supply chain (antibody, payload-linker, conjugation, fill)Viral vector manufacturing (lentiviral, retroviral, AAV)