Loading
Sealed, robot-run machines that turn a patient's blood cells into a CAR-T product with far fewer hands, clean rooms, and mistakes.
Functionally closed, GMP-in-a-box platforms (Miltenyi CliniMACS Prodigy, Lonza Cocoon, Cellares Cell Shuttle, Cytiva Sefia) integrate cell selection, activation, transduction, expansion, and harvest in single-use cassettes. They cut labour and clean-room grade requirements, shorten vein-to-vein time, and are the prerequisite for point-of-care and decentralised manufacturing. Throughput per unit and comparability across sites remain the constraints.
Single-use fluid paths with integrated centrifugation, magnetic selection, incubation, and sensors; process recipes run automatically and log every step for batch release.
Nothing recorded yet: a foundation, or a gap to fill.
Dependencies are what this technology cannot be delivered without: manufacturing steps, instruments, software, upstream methods. See its full chain on the map.
Query for this technology: (TITLE:"Closed automated cell-therapy manufacturing" OR ABSTRACT:"Closed automated cell-therapy manufacturing") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Closed automated cell-therapy manufacturing, not a curated reading list.
Shares Cytiva (Danaher), Single-use bioprocessing systems, Lonza, Autologous CAR-T manufacturing, batch by batch and the tag supporting.
Shares Vein-to-vein time and manufacturing slots, Autologous CAR-T manufacturing, batch by batch, CAR-T cell therapy and the tag supporting.
Shares Terumo Blood and Cell Technologies, Autologous CAR-T manufacturing, batch by batch, CAR-T cell therapy and the tag supporting.
Shares Cell-therapy release and potency testing, Flow cytometers and the tag supporting.
Shares Single-use bioprocessing systems, Flow cytometers and the tag supporting.
Shares Single-use bioprocessing systems, Lonza and the tag supporting.
Shares Cell-therapy release and potency testing and the tag supporting.
Shares Point-of-care and decentralised cell manufacturing and the tag supporting.