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ClinicalTrials.gov
ClinicalTrials.gov is the master list of clinical trials. Every trial on this site links to its record.
Overview
ClinicalTrials.gov is the registry and results database of more than 500,000 clinical studies worldwide, run by the NIH National Library of Medicine and released as public domain US Government work. Registration is mandatory for US trials, and API v2 gives structured access to eligibility criteria, arms, outcome measures and posted results, which makes it the backbone of any trial-matching tool. Every trial on OnCo links to its ClinicalTrials.gov record, and the collection is tied to the technology AI trial matching and clinical decision support. It is also cited by bottleneck records including Trials enrol too few, too slowly, Failures are hidden, Data silos and Weak real-world evidence and registries, and by ideas such as One standing umbrella trial for all rare cancers in a country.
Holds
Registry and results database of >500,000 clinical studies worldwide.
Licence
Public domain (US Government)
Maintainer
NIH / NLM
Similar pages
- CollectionEU Clinical Trials Register / CTIS
Shares One clinical trial application accepted by regulators in every major region, Publish why patients were screened out of each trial, Actually fine sponsors who do not post trial results, A plain-language summary of every cancer trial result within a year.
- CompanyCancer Commons
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- CompanyTempus AI
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- CollectionSEER (Surveillance, Epidemiology, and End Results)
Shares Set trial enrolment targets from who actually gets the disease, and publish progress live, A public map of trial deserts to steer where new sites open, Pay for residual disease tests only inside a trial or registry, Randomise inside the registry that already follows every patient.
- CollectionFDA Oncology Approvals (OCE) & Novel Drug Approvals
Shares Live tracker of the lag from first approval to real availability in every country, Require every oncology candidate to publish how much reaches the brain, Weak real-world evidence and registries, Trials do not represent the people who get cancer.
- IdeaDynamic consent with usage receipts
Shares Patient Data Vault (data-vault.health), AI trial matching & clinical decision support, Patients lack understanding, navigation and agency, Data silos.
- IdeaA shared library of pooled control arms to shrink and speed future trials
Shares A single oncology trial data trust with mandatory deposit within eighteen months, Secrecy and intellectual property block collaboration, Trials enrol too few, too slowly, Trial design, endpoints and cost.
- IdeaPatient-held portable consent for reusing samples and data across studies
Shares A single oncology trial data trust with mandatory deposit within eighteen months, Secrecy and intellectual property block collaboration, Patients lack understanding, navigation and agency, Data silos.
technologies
companies
terms
roadmaps
ideas
A $50 million prize for the first off-patent drug proven to extend cancer survivalA live 'seats available' feed for trial slots, like airline inventoryA plain-language summary of every cancer trial result within a yearA public map of trial deserts to steer where new sites openA public transparency score for every trial sponsor, used by sites and patientsA shared compound library that rare cancer researchers can actually useA single oncology trial data trust with mandatory deposit within eighteen monthsA standing rulebook for one-patient treatmentsActually fine sponsors who do not post trial resultsAn annual map of high-burden questions that nobody is fundingAn open forecasting tournament on which combination trials will succeedAn open knowledge graph linking trials, results, biomarkers, drugs and recommendationsAutomatically detect when a trial changes its outcomes after the factDefault-inclusive eligibility: sponsors must justify every exclusion criterionDeposit trial results as structured data, not just PDFsEnforce individual participant data sharing as a condition of publication and fundingEvery tumour sequencing report lists open, nearby, matched trials pulled liveGuidelines list the open trials at every decision point, updated monthlyLive tracker of the lag from first approval to real availability in every countryMap trial case report forms to the registry standard so trial and routine data joinNo new trial approval until the sponsor has reported its old onesOne clinical trial application accepted by regulators in every major regionOne ethics approval and one consent form for a platform trial across countriesOne national master contract and budget template for all cancer trialsOne standing umbrella trial for all rare cancers in a countryPay for residual disease tests only inside a trial or registryPay investigators for finishing and publishing trials, not for enrolling patientsPool every immunotherapy trial's biomarker data into one commonsPre-register biomarker validation studies the way trials are registeredPublish why patients were screened out of each trialRandomise inside the registry that already follows every patientRequire every oncology candidate to publish how much reaches the brainSet trial enrolment targets from who actually gets the disease, and publish progress liveShared concurrent control arms across sponsors' trials in the same settingStop failing trials earlier with pre-registered aggressive futility rulesTrial matching inside the electronic record at the moment a treatment is chosen
collections
bottlenecks
Open-source projects
All open source in oncology →Open-source projects that are the code behind this collection or publish it, from OnCo's own catalogue: licence and last activity as the repository reported them on the day of the fetch. Listing is not endorsement; check the licence before reuse and the validation before clinical use.
The Clinical Trials Transformation Initiative's relational database of the whole ClinicalTrials.gov registry, refreshed daily and free to query.
Clinical Trials Transformation Initiative, DukeProject page