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Trial results (hazard ratios, confidence intervals, subgroups, toxicities) would be deposited in a computer-readable form so they can be pooled, checked and used by software immediately.
ClinicalTrials.gov results reporting is structured but coarse; journal articles are unstructured; Kaplan-Meier curves are images. The proposal requires deposition of a structured results package (primary and secondary endpoints with estimates and intervals, digitised survival curves or individual patient time-to-event data, subgroup tables, adverse events by grade in CTCAE codes) in a standard schema at publication, enabling automated meta-analysis and living guidelines.
Shares Hazard ratio (HR), Knowledge reaches practice too slowly, Overall survival (OS).
Shares Hazard ratio (HR), Progression-free survival (PFS), Overall survival (OS).
Shares The answer is 17 years, what is the question: understanding time lags in translational research, Knowledge reaches practice too slowly.
Shares Hazard ratio (HR), Progression-free survival (PFS), Overall survival (OS).
Shares ClinicalTrials.gov, Failures are hidden, Knowledge reaches practice too slowly.
Shares The answer is 17 years, what is the question: understanding time lags in translational research, Knowledge reaches practice too slowly.
Shares The answer is 17 years, what is the question: understanding time lags in translational research, Knowledge reaches practice too slowly.
Shares The answer is 17 years, what is the question: understanding time lags in translational research, Knowledge reaches practice too slowly.