Loading
Build a public, machine-readable map connecting every cancer trial to its results, the drugs and biomarkers involved, and the guideline recommendations it supports, with a source for every link.
Evidence in oncology is scattered across registries, papers, labels and guidelines with no shared identifiers. An open knowledge graph (trial identifiers, PICO elements, structured results, drug and biomarker ontologies, guideline recommendations, provenance for each edge) would let software answer 'what is the evidence for drug X in population Y' reproducibly. OncoKB, CIViC, Open Targets and ClinicalTrials.gov are partial graphs; the proposal funds their federation under open licences with a governance body and curation incentives.
Shares Decision support that cites the exact trial and guideline line it relies on, OncoKB, Knowledge reaches practice too slowly.
Shares OncoKB, ClinicalTrials.gov, Knowledge reaches practice too slowly, CIViC.
Shares OncoKB, Knowledge reaches practice too slowly, CIViC.
Shares Decision support that cites the exact trial and guideline line it relies on, Knowledge reaches practice too slowly.
Shares A public API serving the current standard of care for any cancer, stage and biomarker, Decision support that cites the exact trial and guideline line it relies on, Knowledge reaches practice too slowly.
Shares ClinicalTrials.gov, Data silos.
Shares OncoKB, ClinicalTrials.gov, Data silos.
Shares ClinicalTrials.gov, Data silos.