Loading
Machines that measure thousands of proteins at once from tissue or blood, used to find drug targets and early-detection markers.
Mass spectrometry (Thermo Fisher Orbitrap Astral, Bruker timsTOF, SCIEX ZenoTOF) and affinity-based platforms (Olink/Thermo Fisher Explore, SomaLogic/Standard BioTools SomaScan, Alamar NULISA, Nautilus and Quantum-Si single-molecule approaches) deliver deep proteomes; UK Biobank's 50,000-participant Olink dataset and CPTAC's tumour proteogenomics illustrate the discovery value. Clinical proteomic tests remain few.
Peptide fragmentation and mass measurement (bottom-up MS) or barcoded antibody/aptamer pairs read by sequencing or PCR quantify proteins across large dynamic ranges.
Query for this technology: (TITLE:"Proteomics instruments and affinity platforms" OR ABSTRACT:"Proteomics instruments and affinity platforms") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Proteomics instruments and affinity platforms, not a curated reading list.
Shares UK Biobank and the tag supporting.
Shares UK Biobank and the tag supporting.
Shares Thermo Fisher Scientific and the tag supporting.
Shares Bruker (Bruker Spatial Biology) and the tag supporting.
Shares Thermo Fisher Scientific and the tag supporting.
Shares Thermo Fisher Scientific and the tag supporting.
Shares Thermo Fisher Scientific and the tag supporting.
Shares Thermo Fisher Scientific and the tag supporting.