Loading
Spatial biology instruments are machines that map which genes and proteins are active in each part of a tumour slice.
10x Genomics (Visium HD, Xenium), Bruker Spatial Biology (formerly NanoString GeoMx and CosMx), Vizgen (MERSCOPE), Akoya Biosciences (PhenoCycler) and Lunaphore/Bio-Techne (COMET) sell instruments and reagents for spatial transcriptomics and multiplexed protein imaging. Patent litigation reshaped the market (NanoString bankruptcy and acquisition by Bruker, 2024). Clinical use is nascent; the research impact on tumour microenvironment biology is large.
In situ hybridisation with barcoded probes imaged over many cycles, or capture arrays that record position, followed by sequencing.
Nothing recorded yet: a foundation, or a gap to fill.
Dependencies are what this technology cannot be delivered without: manufacturing steps, instruments, software, upstream methods. See its full chain on the map.
Query for this technology: (TITLE:"Spatial biology instruments" OR ABSTRACT:"Spatial biology instruments") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Spatial biology instruments, not a curated reading list.
Shares Bruker (Bruker Spatial Biology) and the tag supporting.
Shares Diagnostics roadmap: stains → gene panels → blood tests that decide treatment and the tag supporting.
Shares Diagnostics roadmap: stains → gene panels → blood tests that decide treatment and the tag supporting.
Shares Diagnostics roadmap: stains → gene panels → blood tests that decide treatment and the tag supporting.
Shares Diagnostics roadmap: stains → gene panels → blood tests that decide treatment and the tag supporting.
Shares Spatial transcriptomics platforms (Visium HD, Xenium, MERFISH, CosMx, CODEX), Spatial transcriptomics.
Shares Spatial transcriptomics platforms (Visium HD, Xenium, MERFISH, CosMx, CODEX), Spatial transcriptomics.
Shares Spatial transcriptomics platforms (Visium HD, Xenium, MERFISH, CosMx, CODEX), 10x Genomics, Single-cell & spatial profiling.
Open-source projects that implement or serve this technology, from OnCo's own catalogue: licence and last activity as the repository reported them on the day of the fetch. Listing is not endorsement; check the licence before reuse and the validation before clinical use.
Gustave Roussy's technology-agnostic pipeline for spatial omics: segmentation, annotation and visualisation for Xenium, MERSCOPE, CosMx and imaging.