Choosing treatment from a map of where each cell type sits in the tumour, not just from a list of its mutations.
Spatial transcriptomics and multiplex imaging show that immune exclusion, stromal barriers and clonal geography predict response in ways bulk sequencing cannot; tertiary lymphoid structures, for example, predict immunotherapy benefit across tumour types. Turning these maps into a clinical assay requires standardisation, lower cost and prospective validation. Today they are correlative science inside trials, not decision tools.
Spatially resolved RNA or protein profiling quantifies the architecture of the tumour microenvironment; machine learning turns that architecture into a predictive score.
Query for this technology: (TITLE:"Spatial-omics-guided treatment selection" OR ABSTRACT:"Spatial-omics-guided treatment selection") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Spatial-omics-guided treatment selection, not a curated reading list.
Shares Paths to cures: interception, eradication, control, Radical oncology: what could change the war by 2035 and the tags frontier, promising.
Shares Owkin, Radical oncology: what could change the war by 2035, Pathology & radiology foundation models and the tags frontier, promising.
Shares Paths to cures: interception, eradication, control, Radical oncology: what could change the war by 2035 and the tags frontier, promising.
Shares Paths to cures: interception, eradication, control, Radical oncology: what could change the war by 2035 and the tags frontier, promising.
Shares Paths to cures: interception, eradication, control, Radical oncology: what could change the war by 2035, Diagnostics roadmap: stains → gene panels → blood tests that decide treatment and the tags frontier, promising.
Shares Paths to cures: interception, eradication, control, Radical oncology: what could change the war by 2035 and the tags frontier, promising.
Shares Paths to cures: interception, eradication, control, Radical oncology: what could change the war by 2035 and the tags frontier, promising.
Shares Paths to cures: interception, eradication, control, Radical oncology: what could change the war by 2035 and the tags frontier, promising.