Southampton's university hospital and the UK's first purpose-built cancer immunology centre, known for antibody engineering and lymphoma trials.
University Hospital Southampton is the tertiary cancer centre for central southern England, and the University of Southampton opened the Centre for Cancer Immunology in 2018, describing it as the UK's first dedicated centre of its kind. Martin Glennie and Mark Cragg's antibody groups defined how Fc receptors and antibody isotype govern anti-CD20, anti-CD40 and other immunomodulatory antibodies, and Peter Johnson led the RATHL trial that established PET-adapted treatment for advanced Hodgkin lymphoma. The Southampton Clinical Trials Unit and CRUK Southampton Centre run national trials in lymphoma, lung and gastrointestinal cancers and in DNA and peptide vaccines. The hospital houses a large children's oncology service and a Wessex regional genomics laboratory.
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-17.
Matched to University Hospital Southampton NHS Foundation Trust, including child institutions. 434 works · 3,990 citations · 78% open access · 11% clinical trials · 3% reviews.
First author of POSH, the UK prospective cohort of young-onset breast cancer that showed germline BRCA carriers did no worse than non-carriers, and the ones with triple-negative disease did better in the first two years.
British surgeon who led BILCAP, the trial that made six months of capecitabine the standard after surgery for bile duct and gallbladder cancer.
Southampton lymphoma specialist who led the RATHL trial of PET-guided therapy in Hodgkin lymphoma and serves as NHS England's National Clinical Director for Cancer.
Shares AMMF, the Cholangiocarcinoma Charity, Precision-Panc, UK specialist HPB cancer centres, Gallbladder cancer.
Shares AMMF, the Cholangiocarcinoma Charity, Precision-Panc, UK specialist HPB cancer centres, Gallbladder cancer.
Shares EUROPAC, Precision-Panc, UK specialist HPB cancer centres, Gallbladder cancer.
Shares EUROPAC, AMMF, the Cholangiocarcinoma Charity, Precision-Panc, UK specialist HPB cancer centres.
Shares Fc engineering / effector function, ADCC (antibody-dependent cellular cytotoxicity), CD20, Chronic lymphocytic leukaemia.
Shares Precision-Panc, UK specialist HPB cancer centres, Gallbladder cancer, Pancreatic ductal adenocarcinoma.
Shares Precision-Panc, UK specialist HPB cancer centres, Gallbladder cancer, Pancreatic ductal adenocarcinoma.
Shares EUROPAC, UK specialist HPB cancer centres, Gallbladder cancer, Pancreatic ductal adenocarcinoma.