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UK specialist HPB cancer centres
Where HPB cancer surgery happens in the UK: about two dozen specialist centres, each with a weekly specialist MDT that takes every treatment decision for gallbladder and bile duct cancer in its region.
Also called: NHS hepato-pancreato-biliary cancer centresHPB specialist centres (NPaCA Table 7)
Overview
NHS England commissions specialist HPB cancer surgery under service specification 2260 (September 2024), which requires a catchment of at least two million people, 150 liver operations a year for cancer and a weekly specialist MDT. The National Pancreatic Cancer Audit identifies the English centres by trust code (Table 7 of its 2025 methodology supplement, sourced from Pancreatic Cancer UK's centre list); Pancreatic Cancer UK also names the Scottish, Welsh and Northern Irish centres and AMMF keeps a parallel list of centres with cholangiocarcinoma expertise. This collection links the centres that have OnCo records; the UK and NHS page for gallbladder cancer lists the rest by name.
Holds
The NHS trusts and health boards that run specialist hepato-pancreato-biliary (HPB) cancer surgery and the specialist MDT for liver, bile duct, gallbladder and pancreatic cancers: 23 English trusts (the National Pancreatic Cancer Audit's Table 7, sourced from Pancreatic Cancer UK), the Scottish regional surgical centres, the South Wales centre and the Belfast Trust.
Maintainer
Pancreatic Cancer UK (list, updated November 2025); NHS England specification 2260 (model)
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Aberdeen Royal InfirmaryAddenbrooke's Hospital, Cambridge University HospitalsAMMF, the Cholangiocarcinoma CharityBelfast Health and Social Care Trust HPB serviceBristol Haematology and Oncology CentreCastle Hill Hospital, Hull (Queen's Centre)Derriford Hospital, University Hospitals PlymouthGlasgow Royal InfirmaryImperial College Healthcare NHS Trust / Imperial College London Cancer ResearchKing's College Hospital, LondonLeeds Cancer Centre, St James's University HospitalLeicester Cancer Research Centre / University Hospitals of LeicesterLiverpool University Hospitals HPB centre (Aintree)Manchester Royal Infirmary HPB UnitMorriston Hospital, SwanseaNewcastle Cancer Centre / Northern Centre for Cancer CareNinewells Hospital, DundeeNottingham University Hospitals Cancer Centre (City Hospital)Oxford Cancer (Oxford University Hospitals and University of Oxford)Pancreatic Cancer UKRaigmore Hospital, InvernessRoyal Blackburn Hospital (East Lancashire HPB MDT)Royal Free Hospital, Royal Free London NHS Foundation TrustRoyal Infirmary of EdinburghRoyal Stoke University HospitalRoyal Surrey County Hospital, GuildfordUniversity College London Hospitals / UCL Cancer InstituteUniversity Hospital CoventryUniversity Hospital of Wales, CardiffUniversity Hospital Southampton / Centre for Cancer ImmunologyUniversity Hospitals Birmingham / University of Birmingham Cancer Research CentreWeston Park Cancer Centre, Sheffield Teaching Hospitals