Oxford's cancer partnership, combining the Churchill Hospital with the university's radiation oncology, Ludwig and early detection institutes and a deep drug and diagnostics spin-out tradition.
Oxford Cancer unites the Oxford University Hospitals cancer and haematology services at the Churchill Hospital with the University of Oxford's Department of Oncology, the Oxford Institute for Radiation Oncology (descended from the Gray Laboratory's hypoxia research), the Ludwig Institute for Cancer Research Oxford branch and the Weatherall Institute of Molecular Medicine. The CRUK Oxford Centre and Oxford Centre for Early Cancer Detection focus on prevention, screening and liquid biopsy, while the Oxford Cancer and Haematology Centre runs early-phase and radiotherapy trials. Oxford science underpins companies such as Immunocore (from Avidex, whose tebentafusp became the first TCR bispecific approved for uveal melanoma) and Oxford Nanopore, and the ChAdOx vaccine platform is being tested for cancer vaccines. Patients access one of the UK's largest haematology and transplant programmes and a growing sarcoma and colorectal service.
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-16.
Matched to Churchill Hospital, including child institutions. 128 works · 1,264 citations · 71% open access · 21% clinical trials · 4% reviews.
Led ProtecT, the trial that showed monitoring, surgery and radiotherapy give equally low prostate cancer death rates at 15 years.
Medical oncologist who co-directs Oxford Cancer, the city-wide partnership between the University of Oxford and Oxford University Hospitals.
The Oxford oncologist who led QUASAR 2 and co-led SCOT, the trial that cut adjuvant chemotherapy for bowel cancer from six months to three without losing benefit.
Statistician behind the Early Breast Cancer Trialists' meta-analyses that set the global evidence base for adjuvant therapy.
Epidemiologist who quantified how smoking kills and invented the meta-analysis methods that established adjuvant cancer therapy.
The oncologist who led COIN, which showed that adding cetuximab to first-line chemotherapy did not extend life even in RAS wild-type bowel cancer, and who ran the UK's molecularly stratified platform trial.
It defines a small group with an excellent prognosis that no repair immunohistochemistry panel or MSI assay will find, and it is the main argument for sequencing rather than staining alone in younger patients.
POLE and POLD1 are now on polyposis and colorectal germline panels, and the paper explains why a patient with many adenomas and an entirely normal mismatch repair panel still needs sequencing.
The number every stage II conversation still uses. It is also the baseline against which ctDNA-guided de-escalation is judged: DYNAMIC halved chemotherapy use in exactly this group without losing recurrence-free survival.
Shares gp100 (PMEL), Immunocore, Tebentafusp, T-cell engagers (bispecific).
Shares Immunocore, Tebentafusp, T-cell engagers (bispecific), Melanoma.
Shares MRC COIN, QUASAR, FOCUS4, Ovarian cancer.
Shares gp100 (PMEL), Tebentafusp, T-cell engagers (bispecific), Melanoma.
Shares gp100 (PMEL), Tebentafusp, T-cell engagers (bispecific), Melanoma.
Shares Freddie C. Hamdy, ProtecT, Prostate cancer.
Shares Immunocore, Tebentafusp, T-cell engagers (bispecific), Ovarian cancer.
Shares SCOT, Precision-Panc, Cancer Research UK, Pancreatic ductal adenocarcinoma.
Open-source projects that this organisation maintains, from OnCo's own catalogue: licence and last activity as the repository reported them on the day of the fetch. Listing is not endorsement; check the licence before reuse and the validation before clinical use.
A haplotype-based variant caller with a dedicated somatic model for tumour-normal and tumour-only calling.