Detroit's NCI comprehensive cancer centre, where the MCF-7 breast cancer cell line was derived in 1973, now part of McLaren Health Care.
Karmanos descends from the Michigan Cancer Foundation, where in 1973 Herbert Soule derived MCF-7, the oestrogen-receptor-positive breast cancer cell line that became the most studied cancer cell model in the world. NCI-designated since 1978, it is Wayne State University's cancer centre and, since 2014, part of McLaren Health Care, giving it a statewide network of cancer sites across Michigan. It has long run one of the larger academic phase 1 programmes and studies cancer in Detroit's predominantly Black population. Karmanos also operates the Detroit metropolitan SEER registry.
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-24.
Matched to The Barbara Ann Karmanos Cancer Institute, including child institutions. 498 works · 7,119 citations · 65% open access · 14% clinical trials · 1% reviews.
Shares NCI-Designated Cancer Centers, Lab models that fail to predict what happens in patients, Trials do not represent the people who get cancer, National Cancer Institute (NIH).
Shares NCI-Designated Cancer Centers, Real-world evidence, Trials do not represent the people who get cancer, National Cancer Institute (NIH).
Shares NCI-Designated Cancer Centers, Trials do not represent the people who get cancer, National Cancer Institute (NIH), HR-positive / HER2-negative breast cancer.
Shares Estrogen receptor (ERα), Endocrine therapy (SERMs, AIs, SERDs), HR-positive / HER2-negative breast cancer.
Shares Estrogen receptor (ERα), Endocrine therapy (SERMs, AIs, SERDs), HR-positive / HER2-negative breast cancer.
Shares NCI-Designated Cancer Centers, Lab models that fail to predict what happens in patients, National Cancer Institute (NIH).
Shares NCI-Designated Cancer Centers, Trials do not represent the people who get cancer, National Cancer Institute (NIH).
Shares NCI-Designated Cancer Centers, Lab models that fail to predict what happens in patients, National Cancer Institute (NIH).