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Radiotherapy trials need physicists to check every plan and central review of every target drawn, which nobody pays for. Fund that infrastructure permanently so trials are faster and results are trustworthy.
A national or international radiotherapy trials infrastructure providing centralised contouring review, plan quality assurance, dosimetry audit, imaging and outcome data platforms and statistical support to academic radiotherapy trials, with core funding rather than per-trial grants. The UK's RTTQA group and CTRad, NRG's IROC and EORTC's RTQA show the model; their capacity limits how many trials can run. Quality assurance is the difference between radiotherapy trials that change practice (CHHiP, PACE, FAST-Forward) and those that fail from protocol deviation, which has measurably worsened outcomes in several past trials.
Shares A regulatory pathway for new radiotherapy techniques modelled on drug development, MR-guided adaptive radiotherapy, Surgery and radiotherapy cure most, get least, SBRT / SABR (stereotactic radiotherapy).
Shares Pay per course of radiotherapy, not per session, so short courses are not penalised, Validate and reimburse AI contouring and planning to expand radiotherapy capacity, A neutral platform trial for radiotherapy plus immunotherapy combinations, Surgery and radiotherapy cure most, get least.
Shares Uwe Oelfke, SBRT / SABR (stereotactic radiotherapy), IMRT / IGRT (modern external beam).
Shares Uwe Oelfke, MR-guided adaptive radiotherapy, Surgery and radiotherapy cure most, get least, SBRT / SABR (stereotactic radiotherapy).
Shares MR-guided adaptive radiotherapy, NRG Oncology, Surgery and radiotherapy cure most, get least, SBRT / SABR (stereotactic radiotherapy).
Shares Validate and reimburse AI contouring and planning to expand radiotherapy capacity, Surgery and radiotherapy cure most, get least, IMRT / IGRT (modern external beam).
Shares A regulatory pathway for new radiotherapy techniques modelled on drug development, Heidelberg University Hospital / NCT / DKFZ.
Shares Heidelberg University Hospital / NCT / DKFZ, MR-guided adaptive radiotherapy, SBRT / SABR (stereotactic radiotherapy).