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Wasting and side-effects kill or stop treatment for a large share of patients but attract almost no dedicated funding. This would create a standing programme for them.
A programme with its own review panel funds cachexia mechanisms (GDF15, inflammatory and neural circuits), interventional trials of anti-cachexia agents and nutrition and exercise bundles, and toxicity science (neuropathy, cardiotoxicity, cytopenias, cognitive effects) with biomarkers and prevention trials. Supportive-care research fails in general panels because it is judged as less innovative; a dedicated pot and reviewers who know the field fixes that. GDF15 antagonists reaching late-phase trials show the biology is tractable.
Shares Benefits of hyperthermic intraperitoneal chemotherapy for patients with serosal invasion in gastric cancer: a meta-analysis of the randomized controlled trials, Structured exercise prescribed like a drug in all curative-intent cancer care, Cardio-oncology, Supportive care and survivorship roadmap: making treatment bearable → proving it extends life → caring for tens of millions afterwards.
Shares Cachexia, toxicity and the limits of the patient, Geriatric assessment, Supportive care and survivorship roadmap: making treatment bearable → proving it extends life → caring for tens of millions afterwards, Exercise & lifestyle oncology.
Shares Cachexia, toxicity and the limits of the patient, Geriatric assessment, Exercise & lifestyle oncology, Toxicity and quality of life are undervalued.
Shares Benefits of hyperthermic intraperitoneal chemotherapy for patients with serosal invasion in gastric cancer: a meta-analysis of the randomized controlled trials, Geriatric assessment, Funding follows fashion, not burden.
Shares Cachexia, toxicity and the limits of the patient, Supportive care and survivorship roadmap: making treatment bearable → proving it extends life → caring for tens of millions afterwards, Exercise & lifestyle oncology, Toxicity and quality of life are undervalued.
Shares Cachexia, toxicity and the limits of the patient, Supportive care and survivorship roadmap: making treatment bearable → proving it extends life → caring for tens of millions afterwards, Toxicity and quality of life are undervalued.
Shares Structured exercise prescribed like a drug in all curative-intent cancer care, Cachexia, toxicity and the limits of the patient, Exercise & lifestyle oncology, Toxicity and quality of life are undervalued.
Shares Structured exercise prescribed like a drug in all curative-intent cancer care, Cachexia, toxicity and the limits of the patient, Exercise & lifestyle oncology.