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The CHALLENGE trial showed a supervised exercise programme improves survival in colon cancer. Extend it to breast, prostate, and lung cancer with the same rigour.
The CHALLENGE trial showed that a supervised exercise programme improves outcomes in colon cancer, and this idea extends the same rigour to breast, prostate and lung cancer, prescribing structured exercise like a drug in all curative-intent care. A three-year programme after curative treatment is expected to improve disease-free survival through insulin and IGF reduction, lower inflammation and immune surveillance. Level-1 evidence now exists, so implementation is the barrier: reimbursement, workforce and adherence. The test is CHALLENGE-design trials in TNBC and prostate cancer with health-economic analysis and digital delivery arms. Being tested at scale, it addresses the bottlenecks Cachexia, toxicity and the limits of the patient and Survivorship and late effects are neglected.
Shares A dose-finding trial for exercise after cancer, CHALLENGE (CCTG CO.21), Structured exercise programmes after curative treatment, The exercise prescription after cancer: the dose the guidelines state.
Shares A dose-finding trial for exercise after cancer, CHALLENGE (CCTG CO.21), Structured exercise programmes after curative treatment, The exercise prescription after cancer: the dose the guidelines state.
Shares CHALLENGE: a structured exercise programme after chemotherapy improves survival in colon cancer, Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment, Exercise & lifestyle oncology, Survivorship and late effects are neglected.
Shares CHALLENGE: a structured exercise programme after chemotherapy improves survival in colon cancer, CHALLENGE (CCTG CO.21), Exercise & lifestyle oncology, Colorectal cancer.
Shares CHALLENGE: a structured exercise programme after chemotherapy improves survival in colon cancer, CHALLENGE (CCTG CO.21), Exercise & lifestyle oncology, Colorectal cancer.
Shares Multimodal prehabilitation for older patients before major cancer surgery, Four weeks of training and nutrition before major cancer surgery, as standard, Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment, Exercise & lifestyle oncology.
Shares Multimodal prehabilitation for older patients before major cancer surgery, Four weeks of training and nutrition before major cancer surgery, as standard, The exercise prescription after cancer: the dose the guidelines state, Survivorship and late effects are neglected.
Shares Multimodal prehabilitation for older patients before major cancer surgery, Four weeks of training and nutrition before major cancer surgery, as standard, The exercise prescription after cancer: the dose the guidelines state, Survivorship and late effects are neglected.