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Trials
KN035 for dMMR/MSI-H Advanced Solid Tumors

trialsTrialRecruiting

KN035 for dMMR/MSI-H Advanced Solid Tumors

A phase 2 trial of Envafolimab in advanced solid tumours, run by 3D Medicines (Sichuan) Co., Ltd., now recruiting.

Overview Connected5

Overview

KN035 for dMMR/MSI-H Advanced Solid Tumors is a phase 2 interventional study registered as NCT03667170 by 3D Medicines (Sichuan) Co., Ltd., with 200 participants planned, started 2018-08-22 and due to reach its primary completion in 2026-12-30. Interventions recorded: KN035.

Setting

Study of KN035 as Monotherapy in Patients With Advanced Mismatched Repair Deficient (dMMR) or Microsatellite Instability-High (MSI-H) Solid Tumors

Phase

Phase 2

Sponsor

3D Medicines (Sichuan) Co., Ltd.

Registry

Started

2018-08-22

Enrolled

200 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

technologies

Immune checkpoint inhibitors Monoclonal antibodies

drugs

ApprovedSingle-domain antibody (anti-PD-L1, subcutaneous)

Envafolimab · Enweida

companies

Evidence strength32/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
200 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT03667170

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Technologies

Immune checkpoint inhibitors
Monoclonal antibodies

Products

Envafolimab

Companies

3D Medicines

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

Machine-readable versions of KN035 for dMMR/MSI-H Advanced Solid Tumors

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MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id nct03667170.

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