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Trials
N-3C01 Monotherapy and Combination With PD-(L)1 Inhibitors in Advanced Solid Tumors

trialsTrialRecruiting

N-3C01 Monotherapy and Combination With PD-(L)1 Inhibitors in Advanced Solid Tumors

A phase 1/2 trial of Pembrolizumab in advanced solid tumours, run by Hefei Xinzhu Biological Technology Co., Ltd., now recruiting.

Overview Connected3

Overview

N-3C01 Monotherapy and Combination With PD-(L)1 Inhibitors in Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT07639450 by Hefei Xinzhu Biological Technology Co., Ltd., with 114 participants planned, started 2026-06-15 and due to reach its primary completion in 2028-08-31. Interventions recorded: N-3C01(Q2W), N-3C01(Q3W), N-3C01 and Pembrolizumab.

Setting

A Phase I/II Clinical Study Evaluating the Safety, Tolerability, and Efficacy of N-3C01 as Monotherapy and in Combination With PD-(L)1 Monoclonal Antibody in Patients With Advanced Malignant Solid Tumors

Phase

Phase 1/2

Sponsor

Hefei Xinzhu Biological Technology Co., Ltd.

Registry

Started

2026-06-15

Enrolled

114 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

technologies

Immune checkpoint inhibitors

drugs

ApprovedMonoclonal antibody (anti-PD-1)

Pembrolizumab · Keytruda / Keytruda Qlex (SC)

Evidence strength23/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
114 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT07639450

Data

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