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Trials
A Study of YL242 in Subjects With Advanced Solid Tumors

trialsTrialRecruiting

A Study of YL242 in Subjects With Advanced Solid Tumors

A phase 1/2 trial of Pembrolizumab in advanced solid tumours, run by MediLink Therapeutics (Suzhou) Co., Ltd., now recruiting.

Overview Connected4

Overview

A Study of YL242 in Subjects With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT07197827 by MediLink Therapeutics (Suzhou) Co., Ltd., with 424 participants planned, started 2025-09-22 and due to reach its primary completion in 2028-09. Interventions recorded: YL242, YL242; Pembrolizumab, YL242; 5-FU; LV and YL242; Pembrolizumab; 5-FU.

Setting

A Phase 1/2, Multicenter, Open-Label, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of YL242 Monotherapy and Combinations in Advanced Solid Tumors.

Phase

Phase 1/2

Sponsor

MediLink Therapeutics (Suzhou) Co., Ltd.

Registry

Started

2025-09-22

Enrolled

424 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

technologies

Immune checkpoint inhibitors

drugs

ApprovedMonoclonal antibody (anti-PD-1)

Pembrolizumab · Keytruda / Keytruda Qlex (SC)

companies

MediLink Therapeutics

Evidence strength26/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
424 enrolled+13
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT07197827

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Technologies

Immune checkpoint inhibitors

Products

Pembrolizumab

Companies

MediLink Therapeutics

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