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Fluid that builds up around the lung (pleural effusion) or in the abdomen (ascites) because cancer cells irritate the lining and block lymph drainage; it causes breathlessness or a swollen, tight belly.
Both are signs of advanced disease (stage IV in lung cancer; a criterion in Child-Pugh and BCLC for liver cancer) and both are diagnosed and relieved by draining the fluid, which can also be sent for cytology and ctDNA. Repeated drainage, indwelling catheters, pleurodesis and, for ascites, diuretics or intraperitoneal therapy are the management options; effective systemic treatment of the cancer is what stops the fluid re-forming. Ovarian cancer classically presents with ascites.
Central tumours arise in the large airways, peripheral ones in the alveoli; both drain to hilar then mediastinal nodes, and the pleural lining is a separate cancer site.
Same organ: Mediastinal germ cell tumour, Pleuropulmonary blastoma (types I, Ir, II and III), Type A and type AB thymoma, Type B1 and type B2 thymoma, Type B3 thymoma, Micronodular thymoma with lymphoid stroma, Adenocarcinoma of the lung, Squamous cell carcinoma of the lung, Large cell carcinoma of the lung, Sarcomatoid carcinoma of the lung, Adenosquamous carcinoma of the lung, Invasive mucinous adenocarcinoma of the lung, Adenocarcinoma in situ and minimally invasive adenocarcinoma of the lung, Basaloid squamous cell carcinoma of the lung, Lymphoepithelial carcinoma of the lung, Pulmonary blastoma (adult), Lung cancer (all types), Small-cell lung cancer, Mesothelioma, Pleural mesothelioma, Thymoma and thymic carcinoma, Childhood lung and airway tumours (pleuropulmonary blastoma, tracheobronchial tumours), Inflammatory myofibroblastic tumour (IMT), EGFR-mutated non-small-cell lung cancer, ALK-positive non-small-cell lung cancer, KRAS G12C-mutant non-small-cell lung cancer, ROS1-positive non-small-cell lung cancer, MET exon 14 and MET-amplified non-small-cell lung cancer, RET fusion-positive non-small-cell lung cancer, BRAF V600E-mutant non-small-cell lung cancer, HER2-mutant non-small-cell lung cancer, NTRK fusion-positive non-small-cell lung cancer, PD-L1-high non-small-cell lung cancer without a driver mutation, Resectable stage I to III non-small-cell lung cancer, Unresectable stage III non-small-cell lung cancer, Limited-stage small-cell lung cancer, Extensive-stage small-cell lung cancer, Lung neuroendocrine tumours (typical and atypical carcinoid), Large cell neuroendocrine carcinoma of the lung, Thymoma (WHO types A, AB, B1, B2 and B3), Thymic carcinoma
Showing the organ this term concerns: Non-small-cell lung cancer.
Shares Pleura, Mesothelioma, Lung cancer (all types), Non-small-cell lung cancer.
Shares Pleura, Mesothelioma, Lung cancer (all types), Non-small-cell lung cancer.
Shares Palliation in lung cancer: breathlessness, pleural effusion, blocked airway, bone and brain, Small-cell lung cancer, Lung cancer (all types), Non-small-cell lung cancer.
Shares Palliation in lung cancer: breathlessness, pleural effusion, blocked airway, bone and brain, Small-cell lung cancer, Lung cancer (all types), Non-small-cell lung cancer.
Shares Malignant pleural effusion, Mesothelioma, Small-cell lung cancer, Lung cancer (all types).
Shares Mesothelioma, Small-cell lung cancer, Lung cancer (all types), Non-small-cell lung cancer.
Shares Mesothelioma, Ovarian cancer, Small-cell lung cancer, Non-small-cell lung cancer.
Shares Mesothelioma, Ovarian cancer, Non-small-cell lung cancer.