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The two-layered lining around each lung. Mesothelioma grows from it, lung and breast cancers spread to it, and fluid collecting between its layers causes breathlessness.
The visceral pleura covers the lung and the parietal pleura lines the chest wall; the potential space between them fills with a malignant pleural effusion in advanced lung, breast and ovarian cancers and lymphoma. Malignant pleural mesothelioma, almost always from asbestos, spreads along the pleural surface; its surgery ranges from extrapleural pneumonectomy (abandoned after MARS 1) to pleurectomy/decortication (questioned by MARS 2). Pleural invasion also upstages lung cancer.
Central tumours arise in the large airways, peripheral ones in the alveoli; both drain to hilar then mediastinal nodes, and the pleural lining is a separate cancer site.
Same organ: Mediastinal germ cell tumour, Pleuropulmonary blastoma (types I, Ir, II and III), Type A and type AB thymoma, Type B1 and type B2 thymoma, Type B3 thymoma, Micronodular thymoma with lymphoid stroma, Adenocarcinoma of the lung, Squamous cell carcinoma of the lung, Large cell carcinoma of the lung, Sarcomatoid carcinoma of the lung, Adenosquamous carcinoma of the lung, Invasive mucinous adenocarcinoma of the lung, Adenocarcinoma in situ and minimally invasive adenocarcinoma of the lung, Basaloid squamous cell carcinoma of the lung, Lymphoepithelial carcinoma of the lung, Pulmonary blastoma (adult), Non-small-cell lung cancer, Lung cancer (all types), Small-cell lung cancer, Pleural mesothelioma, Thymoma and thymic carcinoma, Childhood lung and airway tumours (pleuropulmonary blastoma, tracheobronchial tumours), Inflammatory myofibroblastic tumour (IMT), EGFR-mutated non-small-cell lung cancer, ALK-positive non-small-cell lung cancer, KRAS G12C-mutant non-small-cell lung cancer, ROS1-positive non-small-cell lung cancer, MET exon 14 and MET-amplified non-small-cell lung cancer, RET fusion-positive non-small-cell lung cancer, BRAF V600E-mutant non-small-cell lung cancer, HER2-mutant non-small-cell lung cancer, NTRK fusion-positive non-small-cell lung cancer, PD-L1-high non-small-cell lung cancer without a driver mutation, Resectable stage I to III non-small-cell lung cancer, Unresectable stage III non-small-cell lung cancer, Limited-stage small-cell lung cancer, Extensive-stage small-cell lung cancer, Lung neuroendocrine tumours (typical and atypical carcinoid), Large cell neuroendocrine carcinoma of the lung, Thymoma (WHO types A, AB, B1, B2 and B3), Thymic carcinoma
Showing the organ this term concerns: Mesothelioma.
Shares MARS 2, Mesothelioma.
Shares MARS 2, Mesothelioma.
Shares Asbestos, Non-small-cell lung cancer.
Shares Malignant pleural effusion and ascites, Non-small-cell lung cancer.
Shares Malignant pleural effusion and ascites, Mesothelioma.
Shares Malignant pleural effusion and ascites, Non-small-cell lung cancer.
Shares Malignant pleural effusion, Mesothelioma, Non-small-cell lung cancer.
Shares Mesothelioma, Non-small-cell lung cancer.