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The thin membrane lining the abdominal cavity and covering the bowel. Cancers of the ovary, stomach, colon, appendix and pancreas seed it with small, poorly vascularised deposits that CT under-detects and drugs reach badly, which is why surgery with heated intraperitoneal chemotherapy (HIPEC) is used in appendiceal and selected ovarian cancers.
Peritoneal metastases (carcinomatosis) cause ascites, bowel obstruction and cachexia, are under-detected by CT, and respond poorly to systemic therapy because deposits are small, poorly vascularised and bathed in a protective fluid space. Treatments include cytoreductive surgery with HIPEC (standard in appendiceal and selected ovarian cancers), intraperitoneal chemotherapy and PIPAC, and in gastric cancer the extent of peritoneal disease (P score, cytology) determines resectability. Mesothelioma can also arise from the peritoneum.
Most high-grade ovarian cancers begin at the tip of the fallopian tube; endometrial cancer lines the uterus, cervical cancer starts at the transformation zone; each drains to a different node group.
Same organ: Adenosquamous carcinoma of the cervix, Small cell neuroendocrine carcinoma of the cervix, Bartholin gland carcinoma, Vulvar melanoma, Vaginal melanoma, High-grade serous ovarian cancer, Low-grade serous ovarian cancer, Clear cell ovarian cancer, Mucinous ovarian cancer, Adult granulosa cell tumour of the ovary, Endometrial cancer, Cervical cancer, Vulvar cancer, Gestational trophoblastic neoplasia, Uterine sarcoma, Vaginal cancer, POLE-ultramutated endometrial cancer, Mismatch-repair-deficient endometrial cancer, p53-abnormal endometrial cancer, including uterine serous carcinoma, Endometrial cancer with no specific molecular profile, Advanced or recurrent endometrial cancer, Uterine carcinosarcoma, Early cervical cancer and fertility-sparing surgery, Locally advanced cervical cancer, Recurrent or metastatic cervical cancer, Platinum-sensitive ovarian cancer, Platinum-resistant ovarian cancer, HPV-associated vulvar squamous cell carcinoma, HPV-independent vulvar squamous cell carcinoma (p53-mutant), Vaginal squamous cell carcinoma (HPV-associated), Vaginal adenocarcinoma (including DES-associated clear cell adenocarcinoma), Low-risk gestational trophoblastic neoplasia (FIGO score 0 to 6), High-risk gestational trophoblastic neoplasia (FIGO score 7 or more, including ultra-high-risk), Placental-site trophoblastic tumour and epithelioid trophoblastic tumour
Showing the organ this term concerns: Ovarian cancer.
Shares Mesothelioma, Ovarian cancer, Pancreatic ductal adenocarcinoma, Colorectal cancer.
Shares HIPEC (hyperthermic intraperitoneal chemotherapy), Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Gastric & gastro-oesophageal junction cancer, Ovarian cancer.
Shares Mesothelioma, Gastric & gastro-oesophageal junction cancer, Colorectal cancer.
Shares Malignant pleural effusion and ascites, Mesothelioma.
Shares Mesothelioma, Ovarian cancer, Pancreatic ductal adenocarcinoma, Colorectal cancer.
Shares Mesothelioma, Gastric & gastro-oesophageal junction cancer, Colorectal cancer.
Shares Mesothelioma, Pancreatic ductal adenocarcinoma, Colorectal cancer.
Shares Mesothelioma, Gastric & gastro-oesophageal junction cancer, Colorectal cancer.