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Painful inflammation and ulcers of the mouth and gut lining, because chemotherapy and radiotherapy hit the fast-dividing cells that renew it. It affects most patients on head and neck chemoradiation or transplant conditioning, can make eating impossible, and is the usual reason those patients need feeding tubes and opioid pain relief.
Severe oral mucositis affects most patients receiving head and neck chemoradiation and high-dose conditioning for transplant, and a minority on 5-FU, methotrexate and taxanes; everolimus and other mTOR inhibitors cause a distinct stomatitis prevented by dexamethasone mouthwash (SWISH). Oesophagitis follows thoracic radiotherapy. Management is analgesia (often opioids), oral care, palifermin in transplant, photobiomodulation, and nutritional support; mucositis prolongs hospital stays, causes dose reductions and increases infection through the damaged barrier. It is the classic example of on-target toxicity to normal proliferating tissue.
Showing the technology this term belongs to: Photobiomodulation (low-level laser) for oral mucositis.
Shares Honey for radiation mucositis, Glutamine for mucositis and neuropathy, Oral cryotherapy (ice chips) to prevent mucositis, Photobiomodulation (low-level laser) for oral mucositis.
Shares Living with FOLFIRINOX, NALIRIFOX and gemcitabine with nab-paclitaxel, Living with FOLFOX, CAPOX, FOLFIRI and the EGFR antibodies, DPYD genotyping and DPD phenotyping before fluoropyrimidines, Pancreatic ductal adenocarcinoma.
Shares Honey for radiation mucositis, Glutamine for mucositis and neuropathy, Oral cryotherapy (ice chips) to prevent mucositis, Photobiomodulation (low-level laser) for oral mucositis.
Shares Feeding tube (gastrostomy, PEG, jejunostomy), Dysphagia (difficulty swallowing).
Shares Living with FOLFIRINOX, NALIRIFOX and gemcitabine with nab-paclitaxel, Glutamine for mucositis and neuropathy, Living with FOLFOX, CAPOX, FOLFIRI and the EGFR antibodies, Pancreatic ductal adenocarcinoma.
Shares Photobiomodulation (low-level laser) for oral mucositis, Dry mouth, teeth and taste after head and neck radiotherapy.
Shares Dysphagia (difficulty swallowing), Dry mouth, teeth and taste after head and neck radiotherapy.
Shares Dysphagia (difficulty swallowing), Dry mouth, teeth and taste after head and neck radiotherapy.