Time-restricted eating means eating within a window of 8-12 hours a day and fasting overnight. It improves blood sugar and weight a little; whether it changes cancer risk or recurrence is unknown.
An analysis of the WHEL cohort (JAMA Oncology 2016) found that breast cancer survivors fasting fewer than 13 hours overnight had a higher risk of recurrence (HR 1.36), which launched interest in time-restricted eating (TRE). Randomised trials in people with obesity show modest weight loss (1-4%) and improved glycaemic markers, with little extra benefit over calorie restriction alone. In oncology, feasibility trials in breast and prostate cancer survivors show high adherence and reductions in insulin and weight; no trial has a cancer endpoint. TRE is simple, cheap and low-risk for people without cachexia, which makes it attractive for pragmatic prevention trials, but the recurrence signal remains observational.
Aligning food intake with the circadian day and extending the nightly fast lowers nocturnal glucose and insulin and improves metabolic flexibility, hypothetically reducing growth signalling to residual cancer cells.
Query for this technology: (TITLE:"Time-restricted eating in cancer prevention and survivorship" OR ABSTRACT:"Time-restricted eating in cancer prevention and survivorship") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Time-restricted eating in cancer prevention and survivorship, not a curated reading list.
Shares Chronotherapy: timing treatment to the body clock, Circadian control, Structured exercise programmes after curative treatment, Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment.
Shares Glycaemic index and glycaemic load, WHEL (Women's Healthy Eating and Living), Energy balance, Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment.
Shares Energy balance, Structured exercise programmes after curative treatment, Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment, Prevention we already have is not deployed.
Shares Chronotherapy: timing treatment to the body clock, Circadian control, Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment, Survivorship and late effects are neglected.
Shares WHEL (Women's Healthy Eating and Living), Energy balance, Structured exercise programmes after curative treatment, Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment.
Shares WHEL (Women's Healthy Eating and Living), Energy balance, Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment, Prevention we already have is not deployed.
Shares Metabolic syndrome and insulin resistance, Energy balance, Structured exercise programmes after curative treatment, Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment.
Shares Structured exercise programmes after curative treatment, Diet, exercise and lifestyle roadmap: causes established → interventions that disappointed → exercise proven as treatment, Survivorship and late effects are neglected, HR-positive / HER2-negative breast cancer.