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Eyelashes and eyebrows often fall out with chemotherapy and can be slow to return. Bimatoprost, a glaucoma eye drop approved for thin lashes, applied along the lash line each night increased lash length and thickness in a randomised trial that included people after chemotherapy.
Bimatoprost 0.03 percent, a prostaglandin analogue, was approved by the FDA in 2008 for eyelash hypotrichosis after it was noticed that glaucoma patients grew longer lashes. A randomised, double-masked, vehicle-controlled trial (Glaser et al., British Journal of Dermatology 2015) enrolled adults with idiopathic hypotrichosis and a cohort who had completed chemotherapy at least four weeks earlier; nightly application to the upper lash margin significantly improved lash prominence, length, thickness and darkness by month 4 in both groups, with continued benefit to 12 months and mainly local side effects (conjunctival redness, eyelid skin darkening). Off-label use on eyebrows is common with less evidence. Iris darkening, a known effect of glaucoma drops instilled into the eye, is rare with lash-margin application. Lashes usually regrow unaided within a few months after chemotherapy, so bimatoprost is for those who want faster or fuller return, and is not used during active chemotherapy.
Prostaglandin F2-alpha analogue signalling prolongs the anagen phase and increases the proportion of follicles in growth, lengthening and thickening lashes.
Query for this technology: (TITLE:"Bimatoprost for eyelash and eyebrow regrowth" OR ABSTRACT:"Bimatoprost for eyelash and eyebrow regrowth") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Bimatoprost for eyelash and eyebrow regrowth, not a curated reading list.
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