Loading
ZNF780A (Zinc finger protein 780A) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Nasopharyngeal carcinoma.
May be involved in transcriptional regulation.
IntOGen calls it a driver in 1 cohort (1 activating, 0 loss-of-function), covering Nasopharyngeal Carcinoma.
In plain words · ZNF780A (Zinc finger protein 780A) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Nasopharyngeal carcinoma.
ZNF780A (Zinc finger protein 780A) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Nasopharyngeal carcinoma.
May be involved in transcriptional regulation. Location: Nucleus (UniProt).
No product in this corpus aims at ZNF780A yet. Drugs fit a pocket that exists only in one shape of the mutant protein and hold it there, off.
First described 2004. Earliest sequence paper UniProt cites for the protein: Ota et al, Nat. Genet, 2004, "Complete sequencing and characterization of 21,243 full-length human cDNAs". Source.
Sources: HGNC HGNC:27603 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt O75290 (protein name, function text, keywords and locations (REST API)); IntOGen ZNF780A (driver in 1 cohort (Act 1, LoF 0); Compendium_Cancer_Genes.tsv release 20240920, CC0 1.0)
May be involved in transcriptional regulation. Location: Nucleus (UniProt). Locus 19q13.2 (HGNC).
Query for this target: (TITLE:"ZNF780A" OR ABSTRACT:"ZNF780A" OR TITLE:"zinc finger protein 780A" OR ABSTRACT:"zinc finger protein 780A" OR TITLE:"Zinc finger protein 780A" OR ABSTRACT:"Zinc finger protein 780A" OR TITLE:"ZNF780" OR ABSTRACT:"ZNF780") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about ZNF780A, not a curated reading list.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.