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NUTM2D (NUT family member 2D) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Nasopharyngeal carcinoma.
UniProt has no function text for Q5VT03; HGNC names it "NUT family member 2D".
IntOGen calls it a driver in 1 cohort (1 activating, 0 loss-of-function), covering Nasopharyngeal Carcinoma.
In plain words · NUTM2D (NUT family member 2D) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Nasopharyngeal carcinoma.
NUTM2D (NUT family member 2D) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Nasopharyngeal carcinoma.
UniProt has no function text for Q5VT03; HGNC names it "NUT family member 2D". Locus 10q23.2 (HGNC).
No product in this corpus aims at NUTM2D yet. Drugs fit a pocket that exists only in one shape of the mutant protein and hold it there, off.
First described 2004. Earliest sequence paper UniProt cites for the protein: Deloukas et al, Nature, 2004, "The DNA sequence and comparative analysis of human chromosome 10". Source.
Sources: HGNC HGNC:23447 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q5VT03 (protein name, function text, keywords and locations (REST API)); IntOGen NUTM2D (driver in 1 cohort (Act 1, LoF 0); Compendium_Cancer_Genes.tsv release 20240920, CC0 1.0)
UniProt has no function text for Q5VT03; HGNC names it "NUT family member 2D". Locus 10q23.2 (HGNC).
Query for this target: (TITLE:"NUTM2D" OR ABSTRACT:"NUTM2D" OR TITLE:"NUT family member 2D" OR ABSTRACT:"NUT family member 2D" OR TITLE:"FAM22D" OR ABSTRACT:"FAM22D") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about NUTM2D, not a curated reading list.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.
Shares Nasopharyngeal carcinoma, IntOGen.