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Cancer biologist who directs the National Cancer Institute's Center for Cancer Research, the large intramural research programme in Bethesda.
Senthil K. Muthuswamy is Director of the Center for Cancer Research (CCR), the intramural research programme of the US National Cancer Institute, and a Senior Investigator in its Laboratory of Cancer Biology and Genetics. He pioneered three dimensional organoid culture and co-culture methods for mechanistic, translational and co-clinical studies, and his laboratory defined roles for cell polarity proteins in cancer biology and therapy resistance. His research interests include metastasis, breast and pancreatic cancer and cancer immunotherapy.
| Title | Journal | Year |
|---|---|---|
| Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancer | Breast Cancer Research | 2024 |
| Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids | Nature Medicine | 2015 |
| Organoid Cultures for the Study of Mammary Biology and Breast Cancer: The Promise and Challenges | Cold Spring Harbor Perspectives in Medicine | 2023 |
Shares NCI Center for Cancer Research (intramural programme), National Cancer Institute (NIH), Pancreatic ductal adenocarcinoma.
Shares Breast cancer research and the tag leadership.
Shares HR-positive / HER2-negative breast cancer and the tags leadership, clinician-scientist.
Shares NCI Center for Cancer Research (intramural programme), National Cancer Institute (NIH).
Shares NCI Center for Cancer Research (intramural programme), National Cancer Institute (NIH).
Shares Pancreatic ductal adenocarcinoma and the tags leadership, clinician-scientist.
Shares HR-positive / HER2-negative breast cancer and the tags leadership, clinician-scientist.
Shares Pancreatic ductal adenocarcinoma and the tags leadership, clinician-scientist.