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PF-08634404 is an experimental investigational agent whose form is not stated in the registry from Pfizer in phase 3 trials for colorectal cancer, gastric & gastro-oesophageal junction cancer and oesophageal cancer, with its target not yet stated publicly.
PF-08634404 (SSGJ-707) is an investigational agent whose form is not stated in the registry developed by Pfizer and Sunshine Guojian Pharmaceutical (Shanghai). Its molecular target is not stated in the ClinicalTrials.gov intervention record, and OnCo has not confirmed one from the sponsor's pipeline page. It is the investigational product in 13 recruiting or active industry-led phase 2 and phase 3 interventional cancer trials, including phase 3 studies NCT07222800 (Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer), NCT07392892 (Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer) and NCT07226999 (Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer), in colorectal cancer, gastric & gastro-oesophageal junction cancer, oesophageal cancer, non-small-cell lung cancer and bladder & urothelial cancer. The largest, NCT07222566, plans to enrol 1410 participants with primary completion expected 2029-02-27. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.
Mechanism not stated in the ClinicalTrials.gov record or on the sponsor's pipeline page.
1.One arm of PF-08634404 binds its target on the cancer cell.
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Query for this drug: (TITLE:"PF-08634404" OR ABSTRACT:"PF-08634404" OR TITLE:"SSGJ-707" OR ABSTRACT:"SSGJ-707") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about PF-08634404, not a curated reading list.
Shares Renal cell carcinoma, Bladder & urothelial cancer, Hepatocellular carcinoma, Gastric & gastro-oesophageal junction cancer and the tag pipeline.
Shares Oesophageal cancer, Bladder & urothelial cancer, Hepatocellular carcinoma, Gastric & gastro-oesophageal junction cancer and the tag pipeline.
Shares Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers, Pfizer (incl. Seagen), Non-small-cell lung cancer and the tag pipeline.
Shares Renal cell carcinoma, Oesophageal cancer, Bladder & urothelial cancer, Gastric & gastro-oesophageal junction cancer and the tag pipeline.
Shares Oesophageal cancer, Gastric & gastro-oesophageal junction cancer, Ovarian cancer, Colorectal cancer and the tag pipeline.
Shares Bladder & urothelial cancer, Small-cell lung cancer, Colorectal cancer, Non-small-cell lung cancer and the tag pipeline.
Shares Renal cell carcinoma, Hepatocellular carcinoma, Colorectal cancer, Non-small-cell lung cancer and the tag pipeline.
Shares Gastric & gastro-oesophageal junction cancer, Ovarian cancer, Colorectal cancer, Non-small-cell lung cancer and the tag pipeline.