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Trials
SL-28 for Advanced Solid Tumours

trialsTrialRecruiting

SL-28 for Advanced Solid Tumours

A phase 1/2 trial of SL-28 in pancreatic ductal adenocarcinoma, non-small-cell lung cancer, oesophageal cancer, gastric & gastro-oesophageal junction cancer, hepatocellular carcinoma and bladder & urothelial cancer, run by Second Life Therapeutics, now recruiting.

Overview Connected6

Overview

SL-28 for Advanced Solid Tumours is a phase 1/2 interventional study registered as NCT07341737 by Second Life Therapeutics, with 60 participants planned, started 2026-08-14 and due to reach its primary completion in 2027-01-01. Interventions recorded: SL-28.

Setting

A Phase 1/2, Multicentre, Open-Label, Dose Escalation and Expansion Study to Assess the Safety, Pharmacokinetics, and Preliminary Efficacy of SL-28 in Patients With Advanced Solid Tumours

Phase

Phase 1/2

Sponsor

Second Life Therapeutics

Registry

Started

2026-08-14

Enrolled

60 enrolled

Connected

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cancers

Bladder & urothelial cancer Gastric & gastro-oesophageal junction cancer Hepatocellular carcinoma Non-small-cell lung cancer Oesophageal cancer Pancreatic ductal adenocarcinoma

Evidence strength17/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
60 enrolled+9
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT07341737

Data

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Cancers

Pancreatic ductal adenocarcinoma
Non-small-cell lung cancer
Oesophageal cancer
Gastric & gastro-oesophageal junction cancer
Hepatocellular carcinoma
Bladder & urothelial cancer

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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