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BA3071 is an experimental monoclonal antibody from BioAtla in phase 2 trials for non-small-cell lung cancer and melanoma, aimed at CTLA-4.
BA3071 is a monoclonal antibody developed by BioAtla. Its target is CTLA-4 (the sponsor names CTLA-4). The sponsor states: A Conditionally Active Biologic (CAB-C) anti-CTLA-4 antibody engineered to bind and block CTLA-4 preferentially within the tumour microenvironment (rather than systemically), activating T cells locally to reduce systemic toxicity. ClinicalTrials.gov describes the intervention as: Conditionally active biologic (CAB) antibody that binds to CTLA-4. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial, in non-small-cell lung cancer and melanoma. The largest, NCT05180799, plans to enrol 320 participants with primary completion was scheduled for 2025-03-19 on the registry. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.
A Conditionally Active Biologic (CAB-C) anti-CTLA-4 antibody engineered to bind and block CTLA-4 preferentially within the tumour microenvironment (rather than systemically), activating T cells locally to reduce systemic toxicity. Connects to CTLA-4.
1.BA3071 binds CTLA-4.
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Query for this drug: (TITLE:"BA3071" OR ABSTRACT:"BA3071") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about BA3071, not a curated reading list.
Shares Melanoma, Non-small-cell lung cancer and the tag pipeline.
Shares Melanoma, Non-small-cell lung cancer and the tag pipeline.
Shares Melanoma, Non-small-cell lung cancer and the tag pipeline.
Shares Melanoma, Non-small-cell lung cancer and the tag pipeline.
Shares CTLA-4, Melanoma, Non-small-cell lung cancer and the tag pipeline.
Shares Melanoma, Non-small-cell lung cancer and the tag pipeline.
Shares Melanoma, Non-small-cell lung cancer and the tag pipeline.